The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

Diffusion‐weighted magnetic resonance imaging (DW‐MRI) aims to disentangle multiple
biological signal sources in each imaging voxel, enabling the computation of innovative …

Purpose Cell size is a fundamental characteristic of all tissues, and changes in cell size in
cancer reflect tumor status and response to treatments, such as apoptosis and cell‐cycle …

Background Biologic specificity of diffusion MRI in relation to prostate cancer
aggressiveness may improve by examining separate components of the diffusion MRI …

The goal of the current study is to include transcytolemmal water exchange in MR cell size
imaging using the IMPULSED model for more accurate characterization of tissue cellular …

Purpose Biophysical models of diffusion MRI have been developed to characterize
microstructure in various tissues, but existing models are not suitable for tissue composed of …

This work presents a biophysical model of diffusion and relaxation MRI for prostate called
relaxation vascular, extracellular and restricted diffusion for cytometry in tumours …

Prostate MRI has seen increasing interest in recent years and has led to the development of
new MRI techniques and sequences to improve prostate cancer (PCa) diagnosis which are …

Cytological features such as cell size and intracellular morphology provide fundamental
information on cell status and hence may provide specific information on changes that arise …

Summary The National Cancer Imaging Translational Accelerator (NCITA) is creating a UK
national coordinated infrastructure for accelerated translation of imaging biomarkers for …