Enzymes are the most proficient catalysts, offering much more competitive processes
compared to chemical catalysts. The number of industrial applications for enzymes has …

Enzymes as catalysts in synthetic organic chemistry gained importance in the latter half of
the 20th century, but nevertheless suffered from two major limitations. First, many enzymes …

Enzymes are increasingly being used as biocatalysts in the generation of products that have
until now been derived using traditional chemical processes. Such products range from …

Asymmetric catalysis plays a key role in modern synthetic organic chemistry, with synthetic
catalysts and enzymes being the two available options. During the latter part of the last …

For the planning of an organic synthesis route, the disconnection approach guided by
retrosynthetic analysis of possible intermediates and the chemical reactions involved, back …

There has been much debate about the extent to which mutational epistasis, that is, the
dependence of the outcome of a mutation on the genetic background, constrains …

The old yellow enzyme (OYE) family is a large group of flavin‐dependent redox biocatalysts
with major applications in the industrial reduction of activated alkenes. These enzymes have …

Abstract Machine learning as a form of artificial intelligence consists of algorithms and
statistical models for improving computer performance for different tasks. Training data are …

Directed evolution is an important research activity in synthetic biology and biotechnology.
Numerous reports describe the application of tedious mutation/screening cycles for the …

Diaryl ketones are important building blocks for synthesizing pharmaceuticals and are
generally regarded as “difficult-to-reduce” ketones due to the large steric hindrance of their …