Maternal caffeine consumption and pregnancy outcomes: a narrative review with implications for advice to mothers and mothers-to-be

JE James - BMJ evidence-based medicine, 2021 - ebm.bmj.com
Objectives Caffeine is a habit-forming substance consumed daily by the majority of pregnant
women. Accordingly, it is important that women receive sound evidence-based advice about …

Caffeine and clinical outcomes in premature neonates

VHS Kumar, SE Lipshultz - Children, 2019 - mdpi.com
Caffeine is the most widely used drug by both adults and children worldwide due to its ability
to promote alertness and elevate moods. It is effective in the management of apnea of …

P-gp expression inhibition mediates placental glucocorticoid barrier opening and fetal weight loss

C Ge, D Xu, P Yu, M Fang, J Guo, D Xu, Y Qiao… - BMC medicine, 2021 - Springer
Background Prenatal adverse environments can cause fetal intrauterine growth retardation
(IUGR) and higher susceptibility to multiple diseases after birth, related to multi-organ …

Maternal caffeine intake during pregnancy and childhood growth and overweight: results from a large Norwegian prospective observational cohort study

E Papadopoulou, J Botton, AL Brantsæter, M Haugen… - BMJ open, 2018 - bmjopen.bmj.com
Objectives To study the association between maternal caffeine intake during pregnancy and
the child's weight gain and overweight risk up to 8 years. Design Prospective nationwide …

An insight into the therapeutic potential of major coffee components

MT Islam, S Tabrez, NR Jabir, M Ali… - Current Drug …, 2018 - ingentaconnect.com
Background: The popular drink, coffee (Coffea arabica) is under the great attention of late
because of its promising pharmacological potential. Caffeine (the major constituent of …

Differential expression of placental 11β-HSD2 induced by high maternal glucocorticoid exposure mediates sex differences in placental and fetal development

P Yu, J Zhou, C Ge, M Fang, Y Zhang… - Science of The Total …, 2022 - Elsevier
A variety of adverse environmental factors during pregnancy cause maternal chronic stress.
Caffeine is a common stressor, and its consumption during pregnancy is widespread. Our …

Prenatal caffeine exposure increases the susceptibility to non-alcoholic fatty liver disease in female offspring rats via activation of GR-C/EBPα-SIRT1 pathway

S Hu, L **a, H Luo, Y Xu, H Yu, D Xu, H Wang - Toxicology, 2019 - Elsevier
This study aimed to evaluate female adult offspring induced by prenatal caffeine exposure
(PCE) are susceptible to non-alcoholic fatty liver disease (NAFLD) and to explore the …

Prenatal caffeine exposure induces liver developmental dysfunction in offspring rats

B He, Y Wen, S Hu, G Wang, W Hu… - Journal of …, 2019 - joe.bioscientifica.com
We previously showed that prenatal caffeine exposure (PCE) induces intrauterine growth
retardation (IUGR) and high susceptibility to nonalcoholic fatty liver disease in offspring rats …

The antioxidant resveratrol acts as a non-selective adenosine receptor agonist

A Sanchez-Melgar, JL Albasanz… - Free Radical Biology …, 2019 - Elsevier
Resveratrol (RSV) is a natural polyphenolic antioxidant with a proven protective role in
several human diseases involving oxidative stress, although the molecular mechanism …

cAMP/PKA/EGR1 signaling mediates the molecular mechanism of ethanol-induced inhibition of placental 11β-HSD2 expression

L Yu, J Zhou, G Zhang, W Huang, L Pei, F Lv… - Toxicology and applied …, 2018 - Elsevier
It is known that inhibiting 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) expression
in the placenta can cause fetal over-exposure to maternal glucocorticoids and induce …