Biomarkers for sepsis: more than just fever and leukocytosis—a narrative review

T Barichello, JS Generoso, M Singer, F Dal-Pizzol - Critical Care, 2022 - Springer
A biomarker describes a measurable indicator of a patient's clinical condition that can be
measured accurately and reproducibly. Biomarkers offer utility for diagnosis, prognosis …

[HTML][HTML] Sepsis Biomarkers: Advancements and Clinical Applications—A Narrative Review

RR He, GL Yue, ML Dong, JQ Wang… - International journal of …, 2024 - mdpi.com
Sepsis is now defined as a life-threatening syndrome of organ dysfunction triggered by a
dysregulated host response to infection, posing significant challenges in critical care. The …

Diagnostic accuracy of procalcitonin, neutrophil-lymphocyte count ratio, C-reactive protein, and lactate in patients with suspected bacterial sepsis

L Ljungström, AK Pernestig, G Jacobsson… - PloS one, 2017 - journals.plos.org
Background Early recognition is a key factor to achieve improved outcomes for septic
patients. Combinations of biomarkers, as opposed to single ones, may improve timely …

Diagnostic value of procalcitonin and presepsin for sepsis in critically ill adult patients: a systematic review and meta-analysis

Y Kondo, Y Umemura, K Hayashida, Y Hara… - Journal of Intensive …, 2019 - Springer
Background Early and accurate diagnosis of sepsis is challenging. Although procalcitonin
and presepsin have been identified as potential biomarkers to differentiate between sepsis …

[HTML][HTML] Presepsin: A promising biomarker for the detection of bacterial infections

MY Memar, HB Baghi - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Appropriate recognition of bacterial infections in health care setting is the basis for effective
treatment and control of infectious diseases. The positivity rate of traditional methods is low …

[HTML][HTML] Presepsin as a diagnostic and prognostic biomarker in sepsis

D Velissaris, N Zareifopoulos, V Karamouzos… - Cureus, 2021 - ncbi.nlm.nih.gov
Sepsis is a condition characterized by high morbidity and mortality which is commonly
encountered in an emergency and critical care setting. Despite a substantial body of …

Multi-marker approach using procalcitonin, presepsin, galectin-3, and soluble suppression of tumorigenicity 2 for the prediction of mortality in sepsis

H Kim, M Hur, HW Moon, YM Yun, S Di Somma… - Annals of intensive …, 2017 - Springer
Background Biomarker could be objective and reliable tools to predict mortality in sepsis.
We explored the prognostic utilities of emerging biomarkers in septic patients and …

Presepsin as early marker of sepsis in emergency department: a narrative review

A Piccioni, MC Santoro, T de Cunzo, G Tullo… - Medicina, 2021 - mdpi.com
The diagnosis and treatment of sepsis have always been a challenge for the physician,
especially in critical care setting such as emergency department (ED), and currently sepsis …

Biomarkers for point-of-care diagnosis of sepsis

A Teggert, H Datta, Z Ali - Micromachines, 2020 - mdpi.com
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. In 2017, almost 50 million cases of sepsis were recorded worldwide …

[HTML][HTML] A 2020 review on the role of procalcitonin in different clinical settings: an update conducted with the tools of the evidence based laboratory medicine

AM Azzini, RM Dorizzi, P Sette, M Vecchi… - Annals of …, 2020 - ncbi.nlm.nih.gov
Biomarkers to guide antibiotic treatment decisions have been proposed as an effective way
to enhancing a more appropriate use of antibiotics. As a biomarker, procalcitonin (PCT) has …