Eph receptors and ephrins in cancer progression

EB Pasquale - Nature Reviews Cancer, 2024‏ - nature.com
Evidence implicating Eph receptor tyrosine kinases and their ephrin ligands (that together
make up the 'Eph system') in cancer development and progression has been accumulating …

MiRNA and LncRNA as potential biomarkers in triple-negative breast cancer: a review

SR Volovat, C Volovat, I Hordila, DA Hordila… - Frontiers in …, 2020‏ - frontiersin.org
Noncoding RNAs (ncRNAs) include a diverse range of RNA species, including microRNAs
(miRNAs) and long noncoding RNAs (lncRNAs). MiRNAs, ncRNAs of approximately 19–25 …

Roles of miRNA and IncRNA in triple-negative breast cancer

J Xu, K Wu, Q Jia, X Ding - Journal of Zhejiang University-science b, 2020‏ - Springer
Triple-negative breast cancer (TNBC) is currently the most malignant subtype of breast
cancer without effective targeted therapies, which makes its pathogenesis an important …

[HTML][HTML] Molecular links between central obesity and breast cancer

AA Zimta, AB Tigu, M Muntean, D Cenariu… - International journal of …, 2019‏ - mdpi.com
Worldwide, breast cancer (BC) is the most common malignancy in women, in regard to
incidence and mortality. In recent years, the negative role of obesity during BC development …

The role of miR-200 family in the regulation of hallmarks of cancer

K Klicka, TM Grzywa, A Mielniczuk, A Klinke… - Frontiers in …, 2022‏ - frontiersin.org
MiRNAs are short non-coding RNAs that regulate gene expression post-transcriptionally
contributing to the development of different diseases including cancer. The miR-200 family …

Targeting the KLF5-EphA2 axis can restrain cancer stemness and overcome chemoresistance in basal-like breast cancer

P Zhao, J Sun, X Huang, X Zhang, X Liu… - International …, 2023‏ - pmc.ncbi.nlm.nih.gov
Ephrin type-A receptor 2 (EphA2) is a member of the tyrosine receptor kinases, a family of
membrane proteins recognized as potential anticancer targets. EphA2 highly expressed in a …

Inhibitory effect of melatonin on hypoxia-induced vasculogenic mimicry via suppressing epithelial-mesenchymal transition (EMT) in breast cancer stem cells.

NF Maroufi, M Amiri, BF Dizaji, V Vahedian… - European Journal of …, 2020‏ - Elsevier
Vasculogenic mimicry (VM) play an important role in breast cancer metastasis and anti-
angiogenic drugs resistance. Hypoxia, the epithelial-mesenchymal transition (EMT), and …

The emerging role of miRNA clusters in breast cancer progression

A Kandettu, R Radhakrishnan, S Chakrabarty… - … et Biophysica Acta (BBA …, 2020‏ - Elsevier
Micro RNAs (miRNAs) are small non-coding RNAs that are essential for regulation of gene
expression of the target genes. Large number of miRNAs are organized into defined units …

Triple negative breast cancer in the era of miRNA

H Sabit, E Cevik, H Tombuloglu, S Abdel-Ghany… - Critical reviews in …, 2021‏ - Elsevier
The objective of this review is to elucidate the role of miRNAs in triple negative breast cancer
(TNBC). To achieve our goal, we searched databases such as PubMed, ScienceDirect …

AMP-activated protein kinase: a potential therapeutic target for triple-negative breast cancer

W Cao, J Li, Q Hao, JV Vadgama, Y Wu - Breast Cancer Research, 2019‏ - Springer
Triple-negative breast cancer (TNBC) is an aggressive subset of breast carcinomas that lack
expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal …