The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches

R Gheorghita, I Soldanescu, A Lobiuc… - Frontiers in …, 2024 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been
defined as the greatest global health and socioeconomic crisis of modern times. While most …

Initial immune response after exposure to Mycobacterium tuberculosis or to SARS-COV-2: similarities and differences

A Aiello, S Najafi-Fard, D Goletti - Frontiers in immunology, 2023 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …

[HTML][HTML] Comprehensive review of COVID-19: epidemiology, pathogenesis, advancement in diagnostic and detection techniques, and post-pandemic treatment …

YS Chung, CY Lam, PH Tan, HF Tsang… - International Journal of …, 2024 - mdpi.com
At present, COVID-19 remains a public health concern due to the ongoing evolution of
SARS-CoV-2 and its prevalence in particular countries. This paper provides an updated …

Exploring the Pathophysiology of Long COVID: The Central Role of Low-Grade Inflammation and Multisystem Involvement

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2024 - mdpi.com
Long COVID (LC), also referred to as Post COVID-19 Condition, Post-Acute Sequelae of
SARS-CoV-2 Infection (PASC), and other terms, represents a complex multisystem disease …

Immunomodulatory approaches in managing lung inflammation in COVID‐19: a double‐edge sword

G Verma, M Dhawan, ARA Saied… - Immunity …, 2023 - Wiley Online Library
Introduction The novel coronavirus infectious disease 2019 (COVID‐19) which is caused by
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has emerged as a gigantic …

Pro inflammatory cytokines profiles of patients with long COVID differ between variant epochs

R Ganesh, S Yadav, RT Hurt… - Journal of Primary …, 2024 - journals.sagepub.com
Background: Over 30% of patients with COVID-19 have persistent symptoms that last
beyond 30 days and referred to as Long COVID. Long COVID has been associated with a …

[HTML][HTML] Immune exhaustion in ME/CFS and long COVID

N Eaton-Fitch, P Rudd, T Er, L Hool, L Herrero… - JCI …, 2024 - pmc.ncbi.nlm.nih.gov
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are
debilitating multisystemic conditions sharing similarities in immune dysregulation and …

Low-dose IL-2 therapy in autoimmune diseases: An update review

R Zhang, Y Zhao, X Chen, Z Zhuang, X Li… - … Reviews of Immunology, 2024 - Taylor & Francis
Regulatory T (Treg) cells are essential for maintaining self-immune tolerance. Reduced
numbers or functions of Treg cells have been involved in the pathogenesis of various …

[HTML][HTML] Cytokine Storm in COVID-19: Exploring IL-6 Signaling and Cytokine-Microbiome Interactions as Emerging Therapeutic Approaches

TG Paranga, I Mitu, M Pavel-Tanasa, MF Rosu… - International Journal of …, 2024 - mdpi.com
IL-6 remains a key molecule of the cytokine storms characterizing COVID-19, exerting both
proinflammatory and anti-inflammatory effects. Emerging research underscores the …

Autism spectrum disorder and a possible role of anti-inflammatory treatments: experience in the pediatric allergy/immunology clinic

H Jyonouchi - Frontiers in Psychiatry, 2024 - frontiersin.org
Autism spectrum disorder (ASD1) is a behaviorally defined syndrome encompassing a
markedly heterogeneous patient population. Many ASD subjects fail to respond to the 1st …