[HTML][HTML] Solid lipid nanoparticles for drug delivery: pharmacological and biopharmaceutical aspects

S Scioli Montoto, G Muraca, ME Ruiz - Frontiers in molecular …, 2020 - frontiersin.org
In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of
the original concepts and ideas. There is no doubt that nanoformulations are extremely …

Gelatin nanofibers: Recent insights in synthesis, bio-medical applications and limitations

HR El-Seedi, NS Said, N Yosri, HB Hawash… - Heliyon, 2023 - cell.com
The use of gelatin and gelatin-blend polymers as environmentally safe polymers to
synthesis electrospun nanofibers, has caused a revolution in the biomedical field. The …

Fundamental aspects of lipid-based excipients in lipid-based product development

D Nakmode, V Bhavana, P Thakor, J Madan, PK Singh… - Pharmaceutics, 2022 - mdpi.com
Poor aqueous solubility of drugs is still a foremost challenge in pharmaceutical product
development. The use of lipids in designing formulations provides an opportunity to …

Impact of doubling peptide length on in vivo hydrogel stability and sustained drug release

J Heremans, L Chevillard, M Mannes… - Journal of controlled …, 2022 - Elsevier
Peptide-based hydrogels represent promising systems for the sustained release of different
types of drugs, ranging from small molecules to biologicals. Aiming at subcutaneous …

Testosterone therapy with subcutaneous injections: a safe, practical, and reasonable option

MG Figueiredo, T Gagliano-Jucá… - The Journal of Clinical …, 2022 - academic.oup.com
Context Injections with intramuscular (IM) testosterone esters have been available for almost
8 decades and not only result in predictable serum testosterone levels but are also the most …

Quantifying skin permeation of a novel metformin lotion using modified hydrophilic interaction liquid chromatography

DJ Maloney, J Zhang, S Bhargava, MCV Hogan… - Bioanalysis, 2024 - Taylor & Francis
Aim: This study aimed to quantify the permeation of metformin (Met) lotion through pig ear
skin using high-performance liquid chromatography, specifically hydrophilic interaction …

Rational-based discovery of novel β-carboline derivatives as potential antimalarials: from in silico identification of novel targets to inhibition of experimental cerebral …

FM Alves, JCB Bellei, CS Barbosa, CL Duarte… - Pathogens, 2022 - mdpi.com
Malaria is an infectious disease widespread in underdeveloped tropical regions. The most
severe form of infection is caused by Plasmodium falciparum, which can lead to …

[HTML][HTML] Search for the ideal route of premedication in children.. far from over?

S Sengupta, P Bhattacharya, DS Nag… - Indian Journal of …, 2022 - journals.lww.com
Perioperative anxiety in children has often been associated with diverse implications like
separation anxiety, emergence delirium, enhanced analgesic requirements and subsequent …

Strategies for Targeted Delivery via Structurally Variant Polymeric Nanocarriers

G Chakraborty, M Meher, S Dash, RN Rout… - …, 2023 - Wiley Online Library
The last decade has seen a meteoric rise in studies investigating polymeric aggregates as
nanocarriers. When it comes to morphology, size, functionality, and immunostability …

[HTML][HTML] Rectal Sedation With Ketamine and Midazolam in the Management of Uncooperative Children During Dental Treatment: A Case Series and Method …

H Alzoubi, S Kabbani, A Taleb, N Bshara, MK Altinawi… - Cureus, 2024 - ncbi.nlm.nih.gov
Background In pediatric dentistry, sedation aims to eliminate anxiety to facilitate the
completion of dental procedures. Sedation in children is a multidimensional field that …