From structure to behavior in basolateral amygdala-hippocampus circuits

Y Yang, JZ Wang - Frontiers in neural circuits, 2017 - frontiersin.org
Emotion influences various cognitive processes, including learning and memory. The
amygdala is specialized for input and processing of emotion, while the hippocampus is …

[HTML][HTML] The hippocampal–prefrontal pathway: The weak link in psychiatric disorders?

BP Godsil, JP Kiss, M Spedding, TM Jay - European …, 2013 - Elsevier
While the hippocampal formation and the prefrontal cortex each have a well-established role
in cognitive and mnemonic processes, the extent and manner in which these structures …

[HTML][HTML] Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety

A Adhikari, MA Topiwala, JA Gordon - Neuron, 2010 - cell.com
The ventral hippocampus, unlike its dorsal counterpart, is required for anxiety-like behavior.
The means by which it acts are unknown. We hypothesized that the hippocampus …

Gating of fear in prelimbic cortex by hippocampal and amygdala inputs

F Sotres-Bayon, D Sierra-Mercado, E Pardilla-Delgado… - Neuron, 2012 - cell.com
The prefrontal cortex (PFC) regulates emotional responses, but it is unclear how PFC
integrates diverse inputs to select the appropriate response. We therefore evaluated the …

Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear

R Marek, J **, TD Goode, TF Giustino, Q Wang… - Nature …, 2018 - nature.com
The medial prefrontal cortex (mPFC) has been implicated in the extinction of emotional
memories, including conditioned fear. We found that ventral hippocampal (vHPC) …

Ventral hippocampal projections to the medial prefrontal cortex regulate social memory

ML Phillips, HA Robinson, L Pozzo-Miller - elife, 2019 - elifesciences.org
Inputs from the ventral hippocampus (vHIP) to the medial prefrontal cortex (mPFC) are
implicated in several neuropsychiatric disorders. Here, we show that the vHIP-mPFC …

Somatostatin interneurons facilitate hippocampal-prefrontal synchrony and prefrontal spatial encoding

AI Abbas, MJM Sundiang, B Henoch, MP Morton… - Neuron, 2018 - cell.com
Decreased hippocampal-prefrontal synchrony may mediate cognitive deficits in
schizophrenia, but it remains unclear which cells orchestrate this long-range synchrony …

The amygdala and medial prefrontal cortex: partners in the fear circuit

R Marek, C Strobel, TW Bredy… - The Journal of physiology, 2013 - Wiley Online Library
Fear conditioning and fear extinction are Pavlovian conditioning paradigms extensively
used to study the mechanisms that underlie learning and memory formation. The neural …

Single units in the medial prefrontal cortex with anxiety-related firing patterns are preferentially influenced by ventral hippocampal activity

A Adhikari, MA Topiwala, JA Gordon - Neuron, 2011 - cell.com
The medial prefrontal cortex (mPFC) and ventral hippocampus (vHPC) functionally interact
during innate anxiety tasks. To explore the consequences of this interaction, we examined …

Hippocampal network connectivity and activation differentiates post-traumatic stress disorder from generalized anxiety disorder

AC Chen, A Etkin - Neuropsychopharmacology, 2013 - nature.com
Anxiety disorders are a diverse group of clinical states. Post-traumatic stress disorder
(PTSD) and generalized anxiety disorder (GAD), eg, share elevated anxiety symptoms, but …