Hematopoietic stem cells (HSCs) employ a very unique metabolic pattern to maintain
themselves, while the spectrum of their metabolic adaptations remains incompletely …

Perivascular collagen deposition by activated fibroblasts promotes vascular stiffening and
drives cardiovascular diseases such as pulmonary hypertension (PH). Whether and how …

The amino acid L-serine (Ser) is indispensable for several cellular processes. In addition to
forming part of proteins, Ser is required for the synthesis of other amino acids, nitrogen …

Signaling trough p53is a major cellular stress response mechanism and increases upon
nutrient stresses such as starvation. Here, we show in a human hepatoma cell line that …

The study of metabolic networks in cancer cells is essential for understanding the
fundamental properties of living systems and how metabolic dysregulation plays a role in …