Background Pyroptosis is a new programmed cell death discovered in recent years.
Pyroptosis plays an important role in various diseases. Nevertheless, there are few …

Ischemic stroke (IS) is one of the leading causes of death and disability. Its pathogenesis is
not completely clear, and inflammatory cascade is one of its main pathological processes …

Epilepsy is one of the most common serious brain diseases worldwide. Programmed cell
death (PCD), a cellular self-destruction phenomenon, has been greatly documented in …

Epilepsy, a fairly common neurological disorder, is linked to various sequelae and greatly
impairs the quality of life. Meanwhile, there is evidence to suggest an association between …

The central nervous system regulates all aspects of physiology to some extent.
Neurodegenerative diseases (NDDs) lead to the progressive loss and dysfunction of …

Highlights•NLRP1 and NLRP3 inflammasome activation is involved in epilepsy
development.•Knockout or knockdown of these molecules improves the symptoms of …

Dysfunction of neuronal nitric oxide synthase contributes to neurotoxicity, which triggers cell
death in various neuropathological diseases, including epilepsy. Studies have shown that …

Clinical and experimental data hints that prolonged and repeated epileptic seizures can
lead to molecular, biochemical, metabolic, and structural changes in the brain, a continuous …

Parkia biglobosa (Jacq.) R. Br.(Fabaceae) is a widely distributed tree, used in traditional
medicine to treat amebiasis, hookworm infection, ascariasis, asthma, sterility, dental pain …

Background Pyroptosis, a novel form of programmed cell death, has been implicated in
neurodegeneration diseases. However, its role in status epilepticus (SE)—a condition …