A comprehensive review of topoisomerase inhibitors as anticancer agents in the past decade

X Liang, Q Wu, S Luan, Z Yin, C He, L Yin, Y Zou… - European journal of …, 2019 - Elsevier
The topoisomerase enzymes play an important role in DNA metabolism, and searching for
enzyme inhibitors is an important target in the search for new anticancer drugs. Discovery of …

Discovery of metal-based complexes as promising antimicrobial agents

J Liang, D Sun, Y Yang, M Li, H Li, L Chen - European Journal of Medicinal …, 2021 - Elsevier
The antimicrobial resistance (AMR) is an intractable problem for the world. Metal ions are
essential for the cell process and biological function in microorganisms. Many metal-based …

Promising dual anticancer and antimetastatic action by a Cu (II) complex derived from acylhydrazone on human osteosarcoma models

L Santa Maria de la Parra, AIB Romo… - Inorganic …, 2024 - ACS Publications
Osteosarcoma cancers are becoming more common in children and young adults, and
existing treatments have low efficacy and a very high mortality rate, making it pressing to …

Advances in anticancer alkaloid-derived metallo-chemotherapeutic agents in the last decade: Mechanism of action and future prospects

MF Ansari, HY Khan, S Tabassum, F Arjmand - Pharmacology & …, 2023 - Elsevier
Metal-based complexes have occupied a pioneering niche in the treatment of many chronic
diseases, including various types of cancers. Despite the phenomenal success of cisplatin …

Crystal structure, optical properties, DFT analysis of new morpholine based Schiff base ligands and their copper (II) complexes: DNA, protein docking analyses …

K Dhahagani, MP Kesavan, KGG Vinoth, L Ravi… - Materials Science and …, 2018 - Elsevier
New morpholine derived Schiff base ligands (HL 1 and HL 2) and their Cu (II) complexes
[Cu (L 1) 2](1) and [Cu (L 2) 2](2) have been synthesized and characterized by 1 H NMR, IR …

Facile Approach to Prepare rGO@Fe3O4 Microspheres for the Magnetically Targeted and NIR-responsive Chemo-photothermal Combination Therapy

C Liang, J Song, Y Zhang, Y Guo, M Deng… - Nanoscale Research …, 2020 - Springer
Abstract Near-infrared (NIR)-light responsive graphene have been shown exciting effect on
cancer photothermal ablation therapy. Herein, we report on the preparation of Fe 3 O 4 …

[HTML][HTML] New pyrimidine based ligand capped gold and platinum nano particles: Synthesis, characterization, antimicrobial, antioxidant, DNA interaction and in vitro …

M Sankarganesh, PA Jose, JD Raja… - … of Photochemistry and …, 2017 - Elsevier
In this research work, we have synthesized new pyrimidine based Schiff base ligand, 2-((4, 6-
dimethoxypyrimidine-2-yl) methyleneenamino)-6-methoxyphenol (DPMM) capped gold (Au) …

[PDF][PDF] Anti-pathogenic activity of cu (II) complexes incorporating Schiff bases: a short review

MNA Bitu, MS Hossain, A Zahid… - American Journal of …, 2019 - researchgate.net
Metals contribute important roles in biological system. It is recognized that metals are highly
linked in cellular and subcellular functions. With the application of novel and experienced …

Anticancer Activity and Mechanism of action evaluation of an acylhydrazone Cu (II) complex toward breast cancer cells, spheroids, and mammospheres

LM Balsa, MR Rodriguez, BS Parajón‐Costa… - …, 2022 - Wiley Online Library
The purpose of this work was to screen the anticancer activity and mechanisms of action of
Cu (II)-acylhydrazone complex [Cu (HL)(H2O)](NO3)· H2O,(CuHL), to find a potential novel …

[HTML][HTML] Evaluation of antioxidant, DNA targeting, antimicrobial and cytotoxic studies of imine capped copper and nickel nanoparticles

PA Jose, JD Raja, M Sankarganesh… - Journal of Photochemistry …, 2018 - Elsevier
In this work, we have synthesized pyrimidine derivatives of Schiff base ligand 2-(4, 6-
dimethoxypyrimidin-2-ylimino) methyl)-6-methoxyphenol (DPMM) stabilized copper …