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A comprehensive review of topoisomerase inhibitors as anticancer agents in the past decade
X Liang, Q Wu, S Luan, Z Yin, C He, L Yin, Y Zou… - European journal of …, 2019 - Elsevier
The topoisomerase enzymes play an important role in DNA metabolism, and searching for
enzyme inhibitors is an important target in the search for new anticancer drugs. Discovery of …
enzyme inhibitors is an important target in the search for new anticancer drugs. Discovery of …
Discovery of metal-based complexes as promising antimicrobial agents
J Liang, D Sun, Y Yang, M Li, H Li, L Chen - European Journal of Medicinal …, 2021 - Elsevier
The antimicrobial resistance (AMR) is an intractable problem for the world. Metal ions are
essential for the cell process and biological function in microorganisms. Many metal-based …
essential for the cell process and biological function in microorganisms. Many metal-based …
Promising dual anticancer and antimetastatic action by a Cu (II) complex derived from acylhydrazone on human osteosarcoma models
Osteosarcoma cancers are becoming more common in children and young adults, and
existing treatments have low efficacy and a very high mortality rate, making it pressing to …
existing treatments have low efficacy and a very high mortality rate, making it pressing to …
Advances in anticancer alkaloid-derived metallo-chemotherapeutic agents in the last decade: Mechanism of action and future prospects
Metal-based complexes have occupied a pioneering niche in the treatment of many chronic
diseases, including various types of cancers. Despite the phenomenal success of cisplatin …
diseases, including various types of cancers. Despite the phenomenal success of cisplatin …
Crystal structure, optical properties, DFT analysis of new morpholine based Schiff base ligands and their copper (II) complexes: DNA, protein docking analyses …
New morpholine derived Schiff base ligands (HL 1 and HL 2) and their Cu (II) complexes
[Cu (L 1) 2](1) and [Cu (L 2) 2](2) have been synthesized and characterized by 1 H NMR, IR …
[Cu (L 1) 2](1) and [Cu (L 2) 2](2) have been synthesized and characterized by 1 H NMR, IR …
Facile Approach to Prepare rGO@Fe3O4 Microspheres for the Magnetically Targeted and NIR-responsive Chemo-photothermal Combination Therapy
C Liang, J Song, Y Zhang, Y Guo, M Deng… - Nanoscale Research …, 2020 - Springer
Abstract Near-infrared (NIR)-light responsive graphene have been shown exciting effect on
cancer photothermal ablation therapy. Herein, we report on the preparation of Fe 3 O 4 …
cancer photothermal ablation therapy. Herein, we report on the preparation of Fe 3 O 4 …
[HTML][HTML] New pyrimidine based ligand capped gold and platinum nano particles: Synthesis, characterization, antimicrobial, antioxidant, DNA interaction and in vitro …
In this research work, we have synthesized new pyrimidine based Schiff base ligand, 2-((4, 6-
dimethoxypyrimidine-2-yl) methyleneenamino)-6-methoxyphenol (DPMM) capped gold (Au) …
dimethoxypyrimidine-2-yl) methyleneenamino)-6-methoxyphenol (DPMM) capped gold (Au) …
[PDF][PDF] Anti-pathogenic activity of cu (II) complexes incorporating Schiff bases: a short review
Metals contribute important roles in biological system. It is recognized that metals are highly
linked in cellular and subcellular functions. With the application of novel and experienced …
linked in cellular and subcellular functions. With the application of novel and experienced …
Anticancer Activity and Mechanism of action evaluation of an acylhydrazone Cu (II) complex toward breast cancer cells, spheroids, and mammospheres
The purpose of this work was to screen the anticancer activity and mechanisms of action of
Cu (II)-acylhydrazone complex [Cu (HL)(H2O)](NO3)· H2O,(CuHL), to find a potential novel …
Cu (II)-acylhydrazone complex [Cu (HL)(H2O)](NO3)· H2O,(CuHL), to find a potential novel …
[HTML][HTML] Evaluation of antioxidant, DNA targeting, antimicrobial and cytotoxic studies of imine capped copper and nickel nanoparticles
In this work, we have synthesized pyrimidine derivatives of Schiff base ligand 2-(4, 6-
dimethoxypyrimidin-2-ylimino) methyl)-6-methoxyphenol (DPMM) stabilized copper …
dimethoxypyrimidin-2-ylimino) methyl)-6-methoxyphenol (DPMM) stabilized copper …