Nanoparticles in drug delivery: From history to therapeutic applications
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …
Intranasal drug delivery: opportunities and toxicologic challenges during drug development
LA Keller, O Merkel, A Popp - Drug delivery and translational research, 2022 - Springer
Over the past 10 years, the interest in intranasal drug delivery in pharmaceutical R&D has
increased. This review article summarises information on intranasal administration for local …
increased. This review article summarises information on intranasal administration for local …
Overcoming barriers by local drug delivery with liposomes
Localized or topical administration of drugs may be considered as a potential approach for
overcoming the problems caused by the various biological barriers encountered in drug …
overcoming the problems caused by the various biological barriers encountered in drug …
Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs
Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
Stimuli-responsive In situ gelling system for nose-to-brain drug delivery
The diagnosis and treatment of neurological ailments always remain an utmost challenge for
research fraternity due to the presence of BBB. The intranasal route appeared as an …
research fraternity due to the presence of BBB. The intranasal route appeared as an …
Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …
[HTML][HTML] Design and optimization of curcumin loaded nano lipid carrier system using Box-Behnken design
Herbal antioxidant like curcumin holds great potential to treat neurodegenerative disease
like Alzheimer's disease. However, its therapeutic potency is obstructed due to rapid …
like Alzheimer's disease. However, its therapeutic potency is obstructed due to rapid …
[HTML][HTML] Biomedical applications of microemulsion through dermal and transdermal route
Microemulsions are thermodynamically stable, transparent, colloidal drug carrier system
extensively used by the scientists for effective drug delivery across the skin. It is a …
extensively used by the scientists for effective drug delivery across the skin. It is a …
Recent expansions of novel strategies towards the drug targeting into the brain
The treatment of central nervous system (CNS) disorders always remains a challenge for the
researchers. The presence of various physiological barriers, primarily the blood–brain …
researchers. The presence of various physiological barriers, primarily the blood–brain …
Lactoferrin in aseptic and septic inflammation
Lactoferrin (Lf), a cationic glycoprotein able to chelate two ferric irons per molecule, is
synthesized by exocrine glands and neutrophils. Since the first anti-microbial function …
synthesized by exocrine glands and neutrophils. Since the first anti-microbial function …