[HTML][HTML] Implantable biosensors and their contribution to the future of precision medicine

M Gray, J Meehan, C Ward, SP Langdon… - The Veterinary …, 2018 - Elsevier
Precision medicine can be defined as the prevention, investigation and treatment of
diseases taking individual variability into account. There are multiple ways in which the field …

Predictive and diagnostic biomarkers of anastomotic leakage: a precision medicine approach for colorectal cancer patients

M Gray, JRK Marland, AF Murray, DJ Argyle… - Journal of personalized …, 2021 - mdpi.com
Development of an anastomotic leak (AL) following intestinal surgery for the treatment of
colorectal cancers is a life-threatening complication. Failure of the anastomosis to heal …

Orbit symmetry breaking in MXene implements enhanced soft bioelectronic implants

Y Wu, Y Li, Y Liu, D Zhu, S **ng, N Lambert… - Science …, 2024 - science.org
Bioelectronic implants featuring soft mechanics, excellent biocompatibility, and outstanding
electrical performance hold promising potential to revolutionize implantable technology …

[HTML][HTML] Real-time measurement of tumour hypoxia using an implantable microfabricated oxygen sensor

JRK Marland, ME Gray, C Dunare, EO Blair… - Sensing and Bio …, 2020 - Elsevier
Hypoxia commonly occurs within tumours and is a major cause of radiotherapy resistance.
Clinical outcomes could be improved by locating and selectively increasing the dose …

Ovine pulmonary adenocarcinoma: a unique model to improve lung cancer research

ME Gray, J Meehan, P Sullivan, JRK Marland… - Frontiers in …, 2019 - frontiersin.org
Lung cancer represents a major worldwide health concern; although advances in patient
management have improved outcomes for some patients, overall 5-year survival rates are …

Engineered niches to analyze mechanisms of metastasis and guide precision medicine

AH Morris, SM Orbach, GG Bushnell, RS Oakes… - Cancer research, 2020 - AACR
Cancer metastasis poses a challenging problem both clinically and scientifically, as the
stochastic nature of metastatic lesion formation introduces complexity for both early …

Post-operative monitoring of intestinal tissue oxygenation using an implantable microfabricated oxygen sensor

JRK Marland, ME Gray, DJ Argyle, I Underwood… - Micromachines, 2021 - mdpi.com
Anastomotic leakage (AL) is a common and dangerous post-operative complication
following intestinal resection, causing substantial morbidity and mortality. Ischaemia in the …

Biocompatibility of common implantable sensor materials in a tumor xenograft model

ME Gray, J Meehan, EO Blair, C Ward… - … Research Part B …, 2019 - Wiley Online Library
Real‐time monitoring of tumor microenvironment parameters using an implanted biosensor
could provide valuable information on the dynamic nature of a tumor's biology and its …

In vivo validation of a miniaturized electrochemical oxygen sensor for measuring intestinal oxygen tension

ME Gray, JRK Marland, C Dunare… - American Journal …, 2019 - journals.physiology.org
Recent advances in the fields of electronics and microfabrication techniques have led to the
development of implantable medical devices for use within the field of precision medicine …

Recent Technologies for Transcutaneous Oxygen and Carbon Dioxide Monitoring

S Bernasconi, A Angelucci, A De Cesari, A Masotti… - Diagnostics, 2024 - mdpi.com
The measurement of partial pressures of oxygen (O2) and carbon dioxide (CO2) is
fundamental for evaluating a patient's conditions in clinical practice. There are many ways to …