The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
Ferrocene-containing hybrids as potential anticancer agents: Current developments, mechanisms of action and structure-activity relationships
Cancer is one of the most fatal threatens to human health throughout the world. The major
challenges in the control and eradication of cancers are the continuous emergency of drug …
challenges in the control and eradication of cancers are the continuous emergency of drug …
Click chemistry and radiochemistry: an update
The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …
Advancements in redox-sensitive micelles as nanotheranostics: a new horizon in cancer management
A Sikder, G Vambhurkar, E Amulya… - Journal of Controlled …, 2022 - Elsevier
Abstract World Health Organisation (WHO) delineated cancer as one of the foremost
reasons for mortality with 10 million deaths in the year 2020. Early diagnosis and effective …
reasons for mortality with 10 million deaths in the year 2020. Early diagnosis and effective …
A brief survey on the application of metal-catalyzed azide–alkyne cycloaddition reactions to the synthesis of ferrocenyl-x-1, 2, 3-triazolyl-R (x= none or a linker and R …
K Kowalski - Coordination Chemistry Reviews, 2023 - Elsevier
Cancer is one of the leading causes of death worldwide. This review highlights the
importance of metal-catalyzed azide–alkyne cycloaddition reactions in the synthesis of …
importance of metal-catalyzed azide–alkyne cycloaddition reactions in the synthesis of …
Recent advances in iron-complexes as drug candidates for cancer therapy: Reactivity, mechanism of action and metabolites
In this perspective, we discuss iron-complexes as drug candidates that are promising
alternatives to conventional platinum-based chemotherapies owing to their broad range of …
alternatives to conventional platinum-based chemotherapies owing to their broad range of …
Anticancer boron-containing prodrugs responsive to oxidative stress from the tumor microenvironment
Boronic acid (and ester) prodrugs targeting the overexpressed level of reactive oxygen
species within tumor microenvironment represent a promising area for the discovery of new …
species within tumor microenvironment represent a promising area for the discovery of new …
An Endoplasmic Reticulum Specific Pro‐amplifier of Reactive Oxygen Species in Cancer Cells
HG Xu, M Schikora, M Sisa, S Daum… - Angewandte Chemie …, 2021 - Wiley Online Library
The folding and export of proteins and hydrolysis of unfolded proteins are disbalanced in the
endoplasmic reticulum (ER) of cancer cells, leading to so‐called ER stress. Agents further …
endoplasmic reticulum (ER) of cancer cells, leading to so‐called ER stress. Agents further …
Anticancer potential of ferrocene-containing derivatives: Current and future prospective
Organometallic compounds have gained popularity as potent anti-cancer therapeutic
prospects in recent years. The constant threat of drug-resistant cancer and the limited …
prospects in recent years. The constant threat of drug-resistant cancer and the limited …
Ferrocene-triazole conjugates: do we know why they are biologically active?
M Koszytkowska-Stawińska, W Buchowicz - Dalton Transactions, 2023 - pubs.rsc.org
The bioorganometallic chemistry of ferrocene has been gaining significance in recent years.
This review presents ferrocene-triazole conjugates displaying significant biological …
This review presents ferrocene-triazole conjugates displaying significant biological …