Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Aggregation-induced emission luminogen: role in biopsy for precision medicine

Y Duo, L Han, Y Yang, Z Wang, L Wang… - Chemical …, 2024 - ACS Publications
Biopsy, including tissue and liquid biopsy, offers comprehensive and real-time physiological
and pathological information for disease detection, diagnosis, and monitoring. Fluorescent …

[HTML][HTML] Aggregation-induced emission: An illuminator in the brain

Y Duo, Y Yang, T Xu, R Zhou, R Wang, G Luo… - Coordination Chemistry …, 2023 - Elsevier
The brain is the central control hub of the whole body. Hence, the consequences of brain
diseases can be lethal. Despite the progress in fundamental and clinical research, several …

Diverse interactions between AIEgens and biomolecules/organisms: Advancing from strategic design to precision theranostics

Q Ding, X Xu, Y Li, B Li, Q Saiding, M Gu, W Tao… - Chem, 2024 - cell.com
Fluorophores play a pivotal role in the contemporary biomedical field due to their versatile
interaction with a diverse range of biomolecules and organisms. They are revolutionizing …

Enhancing the stability of antimicrobial peptides: From design strategies to applications

S Xu, P Tan, Q Tang, T Wang, Y Ding, H Fu… - Chemical Engineering …, 2023 - Elsevier
Antimicrobial peptides (AMPs) offer unique advantages due to their membrane-active
antimicrobial mechanisms, which reduce the likelihood of resistance development …

Molecular insights into the phase transition of lysozyme into amyloid nanostructures: Implications of therapeutic strategies in diverse pathological conditions

S Roy, VR Srinivasan, S Arunagiri, N Mishra… - Advances in Colloid and …, 2024 - Elsevier
Lysozyme, a well-known bacteriolytic enzyme, exhibits a fascinating yet complex behavior
when it comes to protein aggregation. Under certain conditions, this enzyme undergoes …

Application of biomarker-derived fluorescent probes for the detection of Alzheimer's disease

H Ding, Z Li, K Luo, Q Gong, X Tian - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
accumulation of beta-amyloid (Aβ) protein and neurofibrillary tangles in the brain, resulting …

ROF‐2 as an Aggregation‐Induced Emission (AIE) Probe for Multi‐Target Amyloid Detection and Screening of Amyloid Inhibitors

Y Tang, D Zhang, J Zheng - Small, 2024 - Wiley Online Library
Misfolding and aggregation of amyloid peptides into β‐structure‐rich fibrils represent pivotal
pathological features in various neurodegenerative diseases, including Alzheimer's disease …

Nanostructured organic photosensitizer aggregates in disease phototheranostics

M Zheng, Q Yang, C Lu, X Wu, W Yan, D Liu - Drug Discovery Today, 2023 - Elsevier
Highlights•Focusing on disease phototheranostic applications of nanostructured organic
photosensitizer aggregates (NOPSAs).•Highlighting diverse NOPSAs including polymer …

Advances in targeted tracking and detection of soluble amyloid-β aggregates as a biomarker of Alzheimer's disease

H Gao, J Chen, Y Huang, R Zhao - Talanta, 2024 - Elsevier
Misfolding and aggregation of amyloid-β (Aβ) peptides are key hallmarks of Alzheimer's
disease (AD). With accumulating evidence suggesting that different Aβ species have varied …