Microglial research has advanced considerably in recent decades yet has been constrained
by a rolling series of dichotomies such as" resting versus activated" and" M1 versus M2." …

Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Neuroinflammation is instigated by the misfiring of immune cells in the central nervous
system (CNS) involving microglia and astrocytes as key cell-types. Neuroinflammation is a …

Microglia are mononuclear phagocytes of mesodermal origin that migrate to the central
nervous system (CNS) during the early stages of embryonic development. After colonizing …

Microglia are emerging as critical regulators of neuronal function and behavior in nearly
every area of neuroscience. Initial reports focused on classical immune functions of …

Microglia, the brain's resident macrophages, help to regulate brain function by removing
dying neurons, pruning non-functional synapses, and producing ligands that support …

Microglia are brain-resident immune cells with a repertoire of functions in the brain.
However, the extent of their interactions with the vasculature and potential regulation of …

Microglia are resident immune cells in the central nervous system (CNS) that are capable of
carrying out prominent and various functions during development and adulthood under both …

Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that
are increasingly recognized to be essential players in the development, homeostasis and …

There has been an explosion of new findings recently giving us insights into the involvement
of microglia in central nervous system (CNS) disorders. A host of new molecular tools and …