NLRP3 inflammasome-targeting nanomicelles for preventing ischemia–reperfusion-induced inflammatory injury
Ischemia–reperfusion (I/R) injury is a disease process that affects several vital organs. There
is widespread agreement that the NLRP3 inflammasome pathway plays a crucial role in the …
is widespread agreement that the NLRP3 inflammasome pathway plays a crucial role in the …
N-Acetyltransferase 9 ameliorates Aβ42-mediated neurodegeneration in the Drosophila eye
P Deshpande, AV Chimata, E Snider, A Singh… - Cell Death & …, 2023 - nature.com
Abstract Alzheimer's disease (AD), a progressive neurodegenerative disorder, manifests as
accumulation of amyloid-beta-42 (Aβ42) plaques and intracellular accumulation of …
accumulation of amyloid-beta-42 (Aβ42) plaques and intracellular accumulation of …
Antioxidant, antimetastatic and apoptotic potential of silver nanoparticles synthesized by leaf and callus extracts of Hyptis suaveolens L.
S Botcha, SD Prattipati - South African Journal of Botany, 2023 - Elsevier
Green synthesis of silver nanoparticles using plant extracts as reducing agents is an
environmental friendly and cost-effective approach. This study aims to provide a detailed …
environmental friendly and cost-effective approach. This study aims to provide a detailed …
Quantifying innervation facilitated by deep learning in wound healing
The peripheral nerves (PNs) innervate the dermis and epidermis, and are suggested to play
an important role in wound healing. Several methods to quantify skin innervation during …
an important role in wound healing. Several methods to quantify skin innervation during …
Exploring the role of N-acetyltransferases in diseases: a focus on N-acetyltransferase 9 in neurodegeneration
P Deshpande, AV Chimata, A Singh - Neural Regeneration …, 2025 - journals.lww.com
Acetyltransferases, required to transfer an acetyl group on protein are highly conserved
proteins that play a crucial role in development and disease. Protein acetylation is a …
proteins that play a crucial role in development and disease. Protein acetylation is a …
Exploring advanced Drosophila cell death techniques and cancer-related studies
D Tendero-Lopez, M Dominguez, ML Uribe - Frontiers in Cell Death, 2024 - frontiersin.org
Cell death is an essential physiological process for the survival of multicellular organisms.
Our understanding of programmed cell death in development, immune function …
Our understanding of programmed cell death in development, immune function …
miR-277 targets the proapoptotic gene-hid to ameliorate Aβ42-mediated neurodegeneration in Alzheimer's model
P Deshpande, CY Chen, AV Chimata, JC Li… - Cell Death & …, 2024 - nature.com
Abstract Alzheimer's disease (AD), an age-related progressive neurodegenerative disorder,
exhibits reduced cognitive function with no cure to date. One of the reasons for AD is the …
exhibits reduced cognitive function with no cure to date. One of the reasons for AD is the …
Targeting the HECTD3-p62 axis increases the radiosensitivity of triple negative breast cancer cells
M Huang, W Liu, Z Cheng, F Li, Y Kong, C Yang… - Cell Death …, 2024 - nature.com
Triple negative breast cancer is the most malignant subtype of breast cancer and current
treatment options are limited. Radiotherapy is one of the primary therapeutic options for …
treatment options are limited. Radiotherapy is one of the primary therapeutic options for …
A cell atlas of the larval Aedes aegypti ventral nerve cord
Mosquito-borne diseases account for nearly 1 million human deaths annually, yet we have a
limited understanding of developmental events that influence host-seeking behavior and …
limited understanding of developmental events that influence host-seeking behavior and …
Transcriptional pausing factor M1BP regulates cellular homeostasis by suppressing autophagy and apoptosis in Drosophila eye
During organogenesis cellular homeostasis plays a crucial role in patterning and growth.
The role of promoter proximal pausing of RNA polymerase II, which regulates transcription of …
The role of promoter proximal pausing of RNA polymerase II, which regulates transcription of …