Zebrafish models of cardiac disease: From fortuitous mutants to precision medicine

JM González-Rosa - Circulation research, 2022‏ - ahajournals.org
Heart disease is the leading cause of death worldwide. Despite decades of research, most
heart pathologies have limited treatments, and often the only curative approach is heart …

New insights into antioxidant peptides: an overview of efficient screening, evaluation models, molecular mechanisms, and applications

Y Zhang, Y Li, Z Quan, P ** of zebrafish psychoactive drug responses
DV Bozhko, VO Myrov, SM Kolchanova… - Progress in Neuro …, 2022‏ - Elsevier
Zebrafish (Danio rerio) are rapidly emerging in biomedicine as promising tools for disease
modelling and drug discovery. The use of zebrafish for neuroscience research is also …

[HTML][HTML] Lipid conjugate dissociation analysis improves the in vivo understanding of lipid-based nanomedicine

WL van Os, L Wielaert, C Alter, D Davidović… - Journal of Controlled …, 2024‏ - Elsevier
Lipid conjugates have advanced the field of lipid-based nanomedicine by promoting active-
targeting (ligand, peptide, antibody), stability (PEGylation), controlled release (lipoid …

High-throughput screening paradigms in ecotoxicity testing: Emerging prospects and ongoing challenges

D Wlodkowic, M Jansen - Chemosphere, 2022‏ - Elsevier
The rapidly increasing number of new production chemicals coupled with stringent
implementation of global chemical management programs necessities a paradigm shift …

Application of zebrafish as a model for anti-cancer activity evaluation and toxicity testing of natural products

Y Shen, R Sheng, R Guo - Pharmaceuticals, 2023‏ - mdpi.com
Develo** natural product-based anti-cancer drugs/agents is a promising way to overcome
the serious side effects and toxicity of traditional chemotherapeutics for cancer treatment …

Exploiting the zebrafish model for sepsis research: Insights into pathophysiology and therapeutic potentials

J He, P Xu, R Chen, M Chen, B Wang… - Drug Design …, 2024‏ - Taylor & Francis
Sepsis, a severe condition instigated by infections, continues to be a primary global cause of
death, typified by systemic inflammation and advancing immune dysfunction …

Patient-derived xenograft: a more standard “Avatar” model in preclinical studies of gastric cancer

M Zeng, C Pi, K Li, L Sheng, Y Zuo, J Yuan… - Frontiers in …, 2022‏ - frontiersin.org
Despite advances in diagnosis and treatment, gastric cancer remains the third most common
cause of cancer-related death in humans. The establishment of relevant animal models of …