Infrared difference spectroscopy probes vibrational changes of proteins upon their
perturbation. Compared with other spectroscopic methods, it stands out by its sensitivity to …

Crossings of electronic potential energy surfaces in nuclear configuration space, known as
conical intersections, determine the rates and outcomes of a large class of photochemical …

A variety of organisms have evolved mechanisms to detect and respond to light, in which the
response is mediated by protein structural changes after photon absorption. The initial step …

Trans-to-cis isomerization, the key reaction in photoactive proteins, usually cannot occur
through the standard one-bond-flip mechanism. Owing to spatial constraints imposed by a …

The mechanistic understanding of protein functions requires insight into the structural and
reaction dynamics. To elucidate these processes, a variety of experimental approaches are …

Conspectus Electronic excited-state phenomena provide a compelling intersection of
fundamental and applied research interests in the chemical sciences. This holds true for …

We characterize the structural and electronic changes during the photoinduced enol–keto
tautomerization of 2-(2′-hydroxyphenyl)-benzothiazole (HBT) in a nonpolar solvent …

Unveiling the nuclear motions of photoreceptor proteins in action is a crucial goal in protein
science in order to understand their elaborate mechanisms and how they achieve optimal …

The first stage in biological signaling is based on changes in the functional state of a
receptor protein triggered by interaction of the receptor with its ligand (s). The light-triggered …

The biological function of phytochromes is triggered by an ultrafast photoisomerization of the
tetrapyrrole chromophore biliverdin between two rings denoted C and D. The mechanism by …