High-throughput anaerobic screening for identifying compounds acting against gut bacteria in monocultures or communities

P Müller, J de la Cuesta-Zuluaga, M Kuhn… - Nature …, 2024 - nature.com
The human gut microbiome is a key contributor to health, and its perturbations are linked to
many diseases. Small-molecule xenobiotics such as drugs, chemical pollutants and food …

[HTML][HTML] A convenient and versatile culturomics platform to expand the human gut culturome of Lachnospiraceae and Oscillospiraceae

N Plomp, L Liu, L Walters, C Bus-Spoor, MT Khan… - Beneficial …, 2024 - brill.com
The human gut microbiota is increasingly being recognised to play an important role in
maintaining health. The families Lachnospiraceae and Oscillospiraceae in particular, are …

Using matrix assisted laser desorption ionisation mass spectrometry combined with machine learning for vaccine authenticity screening

R Clarke, T Bharucha, BY Arman, B Gangadharan… - npj Vaccines, 2024 - nature.com
The global population is increasingly reliant on vaccines to maintain population health with
billions of doses used annually in immunisation programmes. Substandard and falsified …

Non-antibiotic drugs break colonization resistance against pathogenic Gammaproteobacteria

A Grießhammer, J de la Cuesta-Zuluaga, T Zahir… - bioRxiv, 2023 - biorxiv.org
Non-antibiotic drugs can alter the composition of the gut microbiome, with largely undefined
implications for human health. Here we compared the susceptibility of commensal and …

Determination of Pathogens by Electrophoretic and Spectrometric Techniques

B Buszewski, D Błońska, E Kłodzińska… - Critical Reviews in …, 2024 - Taylor & Francis
In modern medical diagnostics, where analytical chemistry plays a key role, fast and
accurate identification of pathogens is becoming increasingly important. Infectious diseases …

Metabolic diversity and responses of anteater clostridial isolates to chitin-based substrates

A Amin, N Modrackova, V Tejnecky… - Frontiers in Veterinary …, 2025 - frontiersin.org
Aim Clostridium species, such as Clostridium perfringens, C. baratii, C. colicanis,
Paraclostridium bifermentans, and Paeniclostridium sordellii, are Gram-positive, anaerobic …

The tracement of origins of aquatic products by characterization of their gut or gill microbiome via MALDI-TOF MS analysis

Y Chu, M Yu, Y Li, S Yang, H Bi - Food Control, 2024 - Elsevier
Tracement of the origin of seafoods and aquatic products is an important issue for avoiding
the falsification of production regions of aquatic products. Herein, by analyzing black tiger …

Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model

J Schumacher, P Mueller, J Sulzer, F Faber, B Molitor… - bioRxiv, 2024 - biorxiv.org
Clostridioides difficile infections often occur after antibiotic use, but they have also been
linked to proton-pump inhibitor (PPI) therapy. The underlying mechanism—whether infection …

Exposure of gut bacterial isolates to the anthelminthic drugs, ivermectin and moxidectin, leads to antibiotic-like phenotypes of growth inhibition and adaptation

J Dommann, J Keiser, J Garneau, A Gandelin… - Communications …, 2024 - nature.com
Due to their broad-spectrum activities, ivermectin and moxidectin are widely used
anthelminthics in veterinary and human medicine. However, ivermectin has recently been …

MSProfileR: An Open-Source Software for Quality Control of Matrix-Assisted Laser Desorption Ionization–Time of Flight Spectra

R Ben Hamouda, B Estellon, K Himet, A Cherif… - Informatics, 2024 - mdpi.com
In the early 2000s, matrix-assisted laser desorption ionization–time of flight mass
spectrometry (MALDI-TOF MS) emerged as a performant and relevant tool for identifying …