IGF2BP3 from physiology to cancer: novel discoveries, unsolved issues, and future perspectives
C Mancarella, K Scotlandi - Frontiers in cell and developmental …, 2020 - frontiersin.org
RNA network control is a key aspect of proper cellular homeostasis. In this context, RNA-
binding proteins (RBPs) play a major role as regulators of the RNA life cycle due to their …
binding proteins (RBPs) play a major role as regulators of the RNA life cycle due to their …
[HTML][HTML] RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer
Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation
Background RNA-binding proteins (RBPs) function as master regulators of gene expression.
Alterations in RBP expression and function are often observed in cancer and influence …
Alterations in RBP expression and function are often observed in cancer and influence …
Organoid models of glioblastoma and their role in drug discovery
Glioblastoma (GBM) is a devastating adult brain cancer with high rates of recurrence and
treatment resistance. Cellular heterogeneity and extensive invasion of surrounding brain …
treatment resistance. Cellular heterogeneity and extensive invasion of surrounding brain …
RNA-binding proteins in cancer drug discovery
Highlights•RNA-binding proteins (RBPs) are essential for tumorigenesis, immune evasion,
invasion, migration and metastasis, hence promising drug targets in cancer therapy.•Small …
invasion, migration and metastasis, hence promising drug targets in cancer therapy.•Small …
[HTML][HTML] Development of glioblastoma organoids and their applications in personalized therapy
C Xu, X Yuan, P Hou, Z Li, C Wang… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Glioblastomas (GBMs) are the brain tumors with the highest malignancy and poorest
prognoses. GBM is characterized by high heterogeneity and resistance to drug treatment …
prognoses. GBM is characterized by high heterogeneity and resistance to drug treatment …
Application of luteolin in neoplasms and nonneoplastic diseases
K Rakoczy, J Kaczor, A Sołtyk, N Szymańska… - International Journal of …, 2023 - mdpi.com
Researchers are amazed at the multitude of biological effects of 3′, 4′, 5, 7-
tetrahydroxyflavone, more commonly known as luteolin, as it simultaneously has antioxidant …
tetrahydroxyflavone, more commonly known as luteolin, as it simultaneously has antioxidant …
RNA-binding proteins in acute leukemias
Acute leukemias are genetic diseases caused by translocations or mutations, which
dysregulate hematopoiesis towards malignant transformation. However, the molecular mode …
dysregulate hematopoiesis towards malignant transformation. However, the molecular mode …
Role of luteolin-induced apoptosis and autophagy in human glioblastoma cell lines
HS Lee, BS Park, HM Kang, JH Kim, SH Shin, IR Kim - Medicina, 2021 - mdpi.com
Background and Objectives: Malignant glioblastoma (GBM) is caused by abnormal
proliferation of glial cells, which are found in the brain. The therapeutic effects of surgical …
proliferation of glial cells, which are found in the brain. The therapeutic effects of surgical …
[HTML][HTML] Bioactive compounds from Actinidia arguta fruit as a new strategy to fight glioblastoma
C Macedo, PC Costa, F Rodrigues - Food Research International, 2024 - Elsevier
In recent years, there has been a significant demand for natural products as a mean of
disease prevention or as an alternative to conventional medications. The driving force for …
disease prevention or as an alternative to conventional medications. The driving force for …