Conspectus Macrocyclic natural products are plentiful in the bacteria, archaea, and
eukaryote domains of life. For the significant advantages that they provide to the producing …

The metathesis reactions, in their various versions, have become a powerful and extremely
valuable tool for the formation of carbon–carbon bonds in organic synthesis. The plethora of …

For numerous enabling features and strategic virtues, contemporary alkyne metathesis is
increasingly recognized as a formidable synthetic tool. Central to this development was the …

In conceptual terms, the first total synthesis of the cytotoxic marine natural product
njaoamine C differs from all known approaches toward related alkaloids of the manzamine …

cis-Delivery of H2 to the π-system of an unsaturated substrate is the canonical course of
metal catalyzed hydrogenation reactions. The semireduction of internal alkynes with the aid …

The hydrogenation of internal alkynes with [Cp* Ru]-based catalysts is distinguished by an
unorthodox stereochemical course in that E-alkenes are formed by trans-delivery of the two …

Insights into the mechanism of the unusual trans‐hydrogenation of internal alkynes
catalyzed by {Cp* Ru} complexes were gained by para‐hydrogen (p‐H2) induced …

[Cp* RuCl] 4 (1) has previously been shown to be the precatalyst of choice for
stereochemically unorthodox trans-hydrometalations of internal alkynes. Experimental and …

A new family of structurally well-defined molybdenum alkylidyne catalysts for alkyne
metathesis, which is distinguished by a tripodal trisilanolate ligand architecture, is …

Although molybdenum alkylidyne complexes such as 1 endowed with triarylsilanolate
ligands are excellent catalysts for alkyne metathesis, they can encounter limitations when …