Background Estimates of the effectiveness of water, sanitation, and hygiene (WASH)
interventions that provide high levels of service on childhood diarrhoea are scarce. We …

Objective A diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and
polyols (FODMAP) is recommended for irritable bowel syndrome (IBS), if general lifestyle …

Network meta-analysis compares different interventions for the same condition, by
combining direct and indirect evidence derived from all eligible studies. Network …

Irritable bowel syndrome (IBS) remains one of the most common gastrointestinal disorders
seen by clinicians in both primary and secondary care. Since publication of the last British …

Objective There are numerous biological therapies and small molecules licensed for luminal
Crohn's disease (CD), but these are often studied in placebo-controlled trials, meaning …

No network meta‐analysis has examined the relative effects of psychotherapies,
pharmacotherapies and their combination in the treatment of adult depression, while this is a …

This chapter provides an overview of the concepts, assumptions and methods that relate to
network meta‐analyses and to the indirect intervention comparisons on which they are built …

Using a novel technique known as network meta-analysis, we synthesized evidence from
492 studies (87,418 participants) to investigate the effectiveness of procedures in changing …

Functional dyspepsia (FD) is a common disorder of gut–brain interaction, affecting
approximately 7% of individuals in the community, with most patients managed in primary …

Importance Cognitive behavior therapy (CBT) has been shown to be effective in the
treatment of acute depression. However, whether CBT can be effectively delivered in …