The daily removal of billions of apoptotic cells in the human body via the process of
efferocytosis is essential for homeostasis. To allow for this continuous efferocytosis, rapid …

Influenza viruses are a major pathogen of both humans and animals. Recent studies using
gene-knockout mice have led to an in-depth understanding of the innate sensors that detect …

The influenza viruses are some of the most important human pathogens, causing substantial
seasonal and pandemic morbidity and mortality. In humans, infection of the lower respiratory …

Viral respiratory infections are a common cause of severe disease, especially in infants,
people who are immunocompromised, and in the elderly. Neutrophils, an important innate …

Gas exchange is the vital function of the lungs. It occurs in the alveoli, where oxygen and
carbon dioxide diffuse across the alveolar epithelium and the capillary endothelium …

Antibodies can impact pathogens in the presence or in the absence of effector cells or
effector molecules such as complement, and experiments can often sort out with precision …

Neutrophils are immune cells that are well known to be present during many types of lung
diseases associated with acute respiratory distress syndrome (ARDS) and may contribute to …

Viruses such as influenza suppress host immune function by a variety of methods. This may
result in significant morbidity through several pathways, including facilitation of secondary …

For acutely lethal influenza infections, the relative pathogenic contributions of direct viral
damage to lung epithelium versus dysregulated immunity remain unresolved. Here, we take …

The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …