Methods of determining optimal cut-point of diagnostic biomarkers with application of clinical data in ROC analysis: an update review

M Hassanzad, K Hajian-Tilaki - BMC Medical Research Methodology, 2024 - Springer
Introduction An important application of ROC analysis is the determination of the optimal cut-
point for biomarkers in diagnostic studies. This comprehensive review provides a framework …

Calprotectin in inflammatory bowel disease

F Khaki-Khatibi, D Qujeq, M Kashifard, S Moein… - Clinica chimica acta, 2020 - Elsevier
The term IBD is usually used for referring to a group of inflammatory gastro-intestinal
diseases (mainly Crohn's disease and ulcerative colitis). Accordingly, IBD arises as a result …

Serum and fecal markers of intestinal inflammation and intestinal barrier permeability are elevated in Parkinson's disease

L Dumitrescu, D Marta, A Dănău, A Lefter… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is characterized by alpha-synuclein misfolding with subsequent
intraneuronal amyloid formation and accumulation, low grade neuroinflammatory changes …

Sleep disturbance in inflammatory bowel disease: prevalence and risk factors–a cross-sectional study

C Marinelli, EV Savarino, I Marsilio, G Lorenzon… - Scientific reports, 2020 - nature.com
Inflammatory bowel diseases (IBD) are chronic relapsing disorders that have a negative
impact on quality of life. They can be highly disabling and have been associated with sleep …

Biochemical biomarkers of mucosal healing for inflammatory bowel disease in adults

M Krzystek-Korpacka, R Kempiński, M Bromke… - Diagnostics, 2020 - mdpi.com
Mucosal healing (MH) is the key therapeutic target of inflammatory bowel disease (IBD). The
evaluation of MH remains challenging, with endoscopy being the golden standard. We …

Zinc and selenium in inflammatory bowel disease: trace elements with key roles?

M Vaghari-Tabari, D Jafari-Gharabaghlou… - … Trace Element Research, 2021 - Springer
Inflammatory bowel disease (IBD) is a chronic inflammatory condition that may emerge at a
young age and often lasts for life. It often goes through phases of recurrence and remission …

MiRNAs and inflammatory bowel disease: An interesting new story

S Moein, M Vaghari‐Tabari, D Qujeq… - Journal of Cellular …, 2019 - Wiley Online Library
Inflammatory bowel disease (IBD), as a chronic and recurrent inflammatory disorder, is
caused by a dysregulated and aberrant immune response to exposed environmental factors …

Polyphenols and inflammatory bowel disease: Natural products with therapeutic effects?

M Vaghari-Tabari, F Alemi, M Zokaei… - Critical Reviews in …, 2024 - Taylor & Francis
Inflammatory bowel disease (IBD) is a long-life disease with periods of recurrence and relief.
Oxidative stress plays an important role in the pathogenesis of this disease. Recent years' …

Melatonin and inflammatory bowel disease: From basic mechanisms to clinical application

M Vaghari-Tabari, S Moein, A Alipourian, D Qujeq… - Biochimie, 2023 - Elsevier
Inflammatory bowel disease is a chronic inflammatory disease and has periods of
recurrence and remission. Improper immune responses to gut flora bacteria, along with …

CRISPR/Cas9 gene editing: A new therapeutic approach in the treatment of infection and autoimmunity

I Mohammadzadeh, D Qujeq, T Yousefi, GA Ferns… - IUBMB …, 2020 - Wiley Online Library
CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR‐
associated protein9) may be viewed as an adaptive bacterial immune system. When a virus …