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Methods of determining optimal cut-point of diagnostic biomarkers with application of clinical data in ROC analysis: an update review
M Hassanzad, K Hajian-Tilaki - BMC Medical Research Methodology, 2024 - Springer
Introduction An important application of ROC analysis is the determination of the optimal cut-
point for biomarkers in diagnostic studies. This comprehensive review provides a framework …
point for biomarkers in diagnostic studies. This comprehensive review provides a framework …
Calprotectin in inflammatory bowel disease
The term IBD is usually used for referring to a group of inflammatory gastro-intestinal
diseases (mainly Crohn's disease and ulcerative colitis). Accordingly, IBD arises as a result …
diseases (mainly Crohn's disease and ulcerative colitis). Accordingly, IBD arises as a result …
Serum and fecal markers of intestinal inflammation and intestinal barrier permeability are elevated in Parkinson's disease
L Dumitrescu, D Marta, A Dănău, A Lefter… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is characterized by alpha-synuclein misfolding with subsequent
intraneuronal amyloid formation and accumulation, low grade neuroinflammatory changes …
intraneuronal amyloid formation and accumulation, low grade neuroinflammatory changes …
Sleep disturbance in inflammatory bowel disease: prevalence and risk factors–a cross-sectional study
C Marinelli, EV Savarino, I Marsilio, G Lorenzon… - Scientific reports, 2020 - nature.com
Inflammatory bowel diseases (IBD) are chronic relapsing disorders that have a negative
impact on quality of life. They can be highly disabling and have been associated with sleep …
impact on quality of life. They can be highly disabling and have been associated with sleep …
Biochemical biomarkers of mucosal healing for inflammatory bowel disease in adults
Mucosal healing (MH) is the key therapeutic target of inflammatory bowel disease (IBD). The
evaluation of MH remains challenging, with endoscopy being the golden standard. We …
evaluation of MH remains challenging, with endoscopy being the golden standard. We …
Zinc and selenium in inflammatory bowel disease: trace elements with key roles?
Inflammatory bowel disease (IBD) is a chronic inflammatory condition that may emerge at a
young age and often lasts for life. It often goes through phases of recurrence and remission …
young age and often lasts for life. It often goes through phases of recurrence and remission …
MiRNAs and inflammatory bowel disease: An interesting new story
Inflammatory bowel disease (IBD), as a chronic and recurrent inflammatory disorder, is
caused by a dysregulated and aberrant immune response to exposed environmental factors …
caused by a dysregulated and aberrant immune response to exposed environmental factors …
Polyphenols and inflammatory bowel disease: Natural products with therapeutic effects?
Inflammatory bowel disease (IBD) is a long-life disease with periods of recurrence and relief.
Oxidative stress plays an important role in the pathogenesis of this disease. Recent years' …
Oxidative stress plays an important role in the pathogenesis of this disease. Recent years' …
Melatonin and inflammatory bowel disease: From basic mechanisms to clinical application
Inflammatory bowel disease is a chronic inflammatory disease and has periods of
recurrence and remission. Improper immune responses to gut flora bacteria, along with …
recurrence and remission. Improper immune responses to gut flora bacteria, along with …
CRISPR/Cas9 gene editing: A new therapeutic approach in the treatment of infection and autoimmunity
CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR‐
associated protein9) may be viewed as an adaptive bacterial immune system. When a virus …
associated protein9) may be viewed as an adaptive bacterial immune system. When a virus …