Exploring potential roles of long non-coding RNAs in cancer immunotherapy: a comprehensive review

A Arshi, E Mahmoudi, F Raeisi… - Frontiers in …, 2024 - frontiersin.org
Cancer treatment has long been fraught with challenges, including drug resistance,
metastasis, and recurrence, making it one of the most difficult diseases to treat effectively …

Modeling and Remodeling the Cell: How Digital Twins and HCMV Can Elucidate the Complex Interactions of Viral Latency, Epigenetic Regulation, and Immune …

H McMahon-Cole, A Johnson, SS Aghamiri… - Current Clinical …, 2023 - Springer
Abstract Purpose of Review Human cytomegalovirus (HCMV), while asymptomatic in most,
causes significant complications during fetal development, following transplant or in …

[PDF][PDF] Immune digital twin blueprint: A comprehensive mechanistic model of the human immune system

R Amin, SS Aghamiri, BL Puniya, L Mayo, D Startsev… - bioRxiv, 2024 - biorxiv.org
The immune system is a complex and dynamic network, crucial for combating infections and
maintaining health. Develo** a comprehensive digital twin of the immune system requires …

[HTML][HTML] Mechanistic modeling of cell viability assays with in silico lineage tracing

A Mutsuddy, JR Huggins, A Amrit, C Erdem… - …, 2024 - pmc.ncbi.nlm.nih.gov
Data from cell viability assays, which measure cumulative division and death events in a
population and reflect substantial cellular heterogeneity, are widely available. However …

Oberflächenanalyse humaner dendritischer Zellen zur Identifikation potentieller Subpopulationen

F Schütz - 2024 - search.proquest.com
Objectives: Blood dendritic cells (DC) have a major regulatory function in innate and ad-
aptive immunity and can be classified into: plasmacytoid DC (pDC), conventional (mye-loid) …

Single Cell Pharmacodynamic Modeling of Cancer Cell Lines

A Mutsuddy - 2024 - tigerprints.clemson.edu
Cancer is one of the leading causes of disease related death worldwide. Since the discovery
of the genomic origins of cancer, targeted therapy has been developed towards specific …

A comprehensive logic-based model of the human immune system to study the dynamics responses to mono-and coinfections

BL Puniya, R Moore, A Mohammed, R Amin, AL Fleur… - bioRxiv, 2020 - biorxiv.org
The human immune system, which protects against pathogens and diseases, is a complex
network of cells and molecules. The effects of complex dynamical interactions of pathogens …

[CITACE][C] Construction of multiplex PCR assay based on the citE2 gene to identity Salmonella Pullorum and its effector SteE in pathogenicity and immunity

Z Liu - 2023 - SNAU