Paclitaxel (Taxol®) is a promising anti-tumor agent with poor water solubility. It is effective for
various cancers especially ovarian and breast cancer. Intravenous administration of a …

Abstract Two‐dimensional gel electrophoresis (2‐DE) with immobilized pH gradients (IPGs)
combined with protein identification by mass spectrometry (MS) is currently the workhorse …

The primary aim of “omic” technologies is the nontargeted identification of all gene products
(transcripts, proteins, and metabolites) present in a specific biological sample. By their …

Western blotting is an analytical method widely used for detecting and (semi‐) quantifying
specific proteins in given samples. Western blots are continuously applied and developed …

The electrospun fiber mat for drug delivery is a novel formulation with promising clinical
applications in the future. The influence of the solubility and compatibility of drugs in the …

A comparative study on the three quantitative methods frequently used in proteomics, 2D
DIGE (difference gel electrophoresis), cICAT (cleavable isotope-coded affinity tags) and …

Two‐dimensional gel electrophoresis (2‐DE) is widely applied and remains the method of
choice in proteomics; however, pervasive 2‐DE‐related concerns undermine its prospects …

Bile acids (BA), the major components of bile, are biological detergents that facilitate the
emulsification and solubilization of dietary lipids and also display potent antimicrobial …

Local protein synthesis plays a key role in regulating stimulus-induced responses in
dendrites and axons. Recent genome-wide studies have revealed that thousands of different …

Doxorubicin is considered to be the most effective agent in the treatment of breast cancer
patients. Unfortunately, resistance to this agent is common, representing a major obstacle to …