Recent advances in amphotericin B delivery strategies for the treatment of leishmaniases

JS Lanza, S Pomel, PM Loiseau… - Expert opinion on drug …, 2019 - Taylor & Francis
Introduction: Among the drugs in clinical use for the treatment of leishmaniases,
amphotericin B (AmB) is the most effective and has been the most extensively studied for the …

Road map to the treatment of neglected tropical diseases: Nanocarriers interventions

G Joshi, SS Quadir, KS Yadav - Journal of Controlled Release, 2021 - Elsevier
Neglected tropical disease (NTD) is a set of 20 deadliest endemic diseases which shows its
presence in most of the develo** countries worldwide. Nearly 1 billion of the population …

Green synthesis of zinc oxide nanoparticles by Neem extract as multi-facet therapeutic agents

MF Sohail, M Rehman, SZ Hussain, ZE Huma… - Journal of Drug Delivery …, 2020 - Elsevier
This study was designed to develop green synthesized zinc oxide nanoparticles (ZnO-NPs)
as potential nano-antibiotics against drug resistant microbes along with multifarious …

Formulation of amphotericin B in PEGylated liposomes for improved treatment of cutaneous leishmaniasis by parenteral and oral routes

GS Ramos, VMR Vallejos, GSM Borges, RM Almeida… - Pharmaceutics, 2022 - mdpi.com
Liposomal amphotericin B (AmB) or AmBisome® is the most effective and safe therapeutic
agent for visceral leishmaniasis (VL), but its clinical efficacy is limited in cutaneous …

Therapeutic Potential of Quercetin-Loaded Nanoemulsion against Experimental Visceral Leishmaniasis: In Vitro/Ex Vivo Studies and Mechanistic Insights

SS Das, AK Dubey, PRP Verma, SK Singh… - Molecular …, 2022 - ACS Publications
Visceral leishmaniasis (VL) is one of the most fatal and neglected tropical diseases caused
by Leishmania donovani (L. donovani). The applications of currently available …

[HTML][HTML] Design of Mannose-Coated Rifampicin nanoparticles modulating the immune response and Rifampicin induced hepatotoxicity with improved oral drug …

A Rauf, TA Tabish, IM Ibrahim, MR ul Hassan… - Arabian Journal of …, 2021 - Elsevier
We have demonstrated the enhanced in vivo oral efficacy and enhanced hepatoprotective
effects of preactivated thiolated chitosan (Cht) nanoparticles (NPs) for tuberculosis. The …

Nanotechnology approaches for delivery and targeting of Amphotericin B in fungal and parasitic diseases

M Jafari, SS Abolmaali, AM Tamaddon… - …, 2021 - Taylor & Francis
Amphotericin B (AMB), with widespread antifungal and anti-parasitic activities and low cross-
resistance with other drugs, has long been identified as a potent antimicrobial drug …

PEGylated and functionalized polylactide-based nanocapsules: An overview

MA de Oliveira, RS Araújo, VCF Mosqueira - International Journal of …, 2023 - Elsevier
Polymeric nanocapsules (NC) are versatile mixed vesicular nanocarriers, generally
containing a lipid core with a polymeric wall. They have been first developed over four …

Review of novel oral amphotericin B formulations for the treatment of parasitic infections

E Wasan, T Mandava, P Crespo-Moran, A Nagy… - Pharmaceutics, 2022 - mdpi.com
Amphotericin B (AmpB) is a polyene macrolide antibiotic used in the treatment of blood-
borne parasitic and fungal infections. However, its use, particularly in the develo** world …

Development and characterization of bioadhesive film embedded with lignocaine and calcium fluoride nanoparticles

H Ghafar, MI Khan, HS Sarwar, S Yaqoob… - Aaps Pharmscitech, 2020 - Springer
The formation of biofilm by Streptococcus mutans on the tooth surface is the primary cause
of dental caries and periodontal diseases, and fluoride (F) has shown tremendous potential …