COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up: JACC State-of-the-Art Review

B Bikdeli, MV Madhavan, D Jimenez, T Chuich… - Journal of the American …, 2020 - jacc.org
Abstract Coronavirus disease-2019 (COVID-19), a viral respiratory illness caused by the
severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), may predispose patients …

Interventional therapies for pulmonary embolism

F Götzinger, L Lauder, ASP Sharp, IM Lang… - Nature Reviews …, 2023 - nature.com
Pulmonary embolism (PE) is the leading cause of in-hospital death and the third most
frequent cause of cardiovascular death. The clinical presentation of PE is variable, and …

Indigo aspiration system for treatment of pulmonary embolism: results of the EXTRACT-PE trial

AK Sista, JM Horowitz, VF Tapson, M Rosenberg… - Cardiovascular …, 2021 - jacc.org
Objectives This study sought to prospectively evaluate the safety and efficacy of the Indigo
aspiration system in submassive acute pulmonary embolism (PE). Background PE treatment …

[HTML][HTML] Percutaneous treatment options for acute pulmonary embolism: a clinical consensus statement by the ESC Working Group on Pulmonary Circulation and …

P Pruszczyk, FA Klok, N Kucher, M Roik… - …, 2022 - ncbi.nlm.nih.gov
There is a growing clinical and scientific interest in catheter-directed therapy (CDT) of acute
pulmonary embolism (PE). Currently, CDT should be considered for patients with high-risk …

Outcomes in high-risk pulmonary embolism patients undergoing FlowTriever mechanical thrombectomy or other contemporary therapies: results from the FLAME …

MJ Silver, CM Gibson, J Giri, S Khandhar… - Circulation …, 2023 - Am Heart Assoc
Background: Hemodynamically unstable high-risk, or massive, pulmonary embolism (PE)
has a reported in-hospital mortality of over 25%. Systemic thrombolysis is the guideline …

[HTML][HTML] Acute outcomes for the full US cohort of the FLASH mechanical thrombectomy registry in pulmonary embolism

C Toma, WA Jaber, MD Weinberg, MC Bunte… - …, 2023 - ncbi.nlm.nih.gov
Aims We aimed to evaluate the acute safety and effectiveness of mechanical thrombectomy
for intermediate-and high-risk PE in a large real-world population. Methods FLASH is a …

Randomized trial comparing standard versus ultrasound-assisted thrombolysis for submassive pulmonary embolism: the SUNSET sPE trial

ED Avgerinos, W Jaber, J Lacomis, K Markel… - Cardiovascular …, 2021 - jacc.org
Objectives The aim of this trial was to determine whether ultrasound-assisted thrombolysis
(USAT) is superior to standard catheter-directed thrombolysis (SCDT) in pulmonary arterial …

Percutaneous mechanical thrombectomy in a real‐world pulmonary embolism population: Interim results of the FLASH registry

C Toma, MC Bunte, KH Cho, WA Jaber… - Catheterization and …, 2022 - Wiley Online Library
Abstract Objectives The FlowTriever All‐Comer Registry for Patient Safety and
Hemodynamics (FLASH) is a prospective multi‐center registry evaluating the safety and …

Advanced Management of Intermediate- and High-Risk Pulmonary Embolism: JACC Focus Seminar

G Piazza - Journal of the American College of Cardiology, 2020 - jacc.org
Intermediate-risk (submassive) pulmonary embolism (PE) describes normotensive patients
with evidence of right ventricular compromise, whereas high-risk (massive) PE comprises …

Large-bore mechanical thrombectomy versus catheter-directed thrombolysis in the management of intermediate-risk pulmonary embolism: primary results of the …

WA Jaber, CF Gonsalves, S Stortecky, S Horr… - Circulation, 2024 - ahajournals.org
Background: There is a lack of randomized controlled trial (RCT) data comparing outcomes
of different catheter-based interventions for intermediate-risk pulmonary embolism (PE) …