HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management

M Lechner, J Liu, L Masterson, TR Fenton - Nature reviews Clinical …, 2022 - nature.com
Abstract Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …

[HTML][HTML] Biological and clinical aspects of HPV-related cancers

KA Szymonowicz, J Chen - Cancer biology & medicine, 2020 - ncbi.nlm.nih.gov
Cancer-related diseases represent the second overall cause of death worldwide. Human
papilloma virus (HPV) is an infectious agent which is mainly sexually transmitted and may …

Sexually transmitted infections among US women and men: prevalence and incidence estimates, 2018

KM Kreisel, IH Spicknall, JW Gargano… - Sexually transmitted …, 2021 - journals.lww.com
Background The most recent estimates of the number of prevalent and incident sexually
transmitted infections (STIs) in the United States were for 2008. We provide updated …

Investigating immune and non-immune cell interactions in head and neck tumors by single-cell RNA sequencing

CHL Kürten, A Kulkarni, AR Cillo, PM Santos… - Nature …, 2021 - nature.com
Head and neck squamous cell carcinoma (HNSCC) is characterized by complex relations
between stromal, epithelial, and immune cells within the tumor microenvironment (TME). To …

Block copolymer micelles in nanomedicine applications

H Cabral, K Miyata, K Osada, K Kataoka - Chemical reviews, 2018 - ACS Publications
Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

The natural history of human papillomavirus infection

S de Sanjose, M Brotons, MA Pavon - Best practice & research Clinical …, 2018 - Elsevier
Human papillomavirus (HPV) is a small double-stranded DNA virus that commonly infects
humans. The oncogenic characteristics of HPV derive from the oncoproteins E6 and E7 that …

Carcinogenic human papillomavirus infection

M Schiffman, J Doorbar, N Wentzensen… - Nature reviews Disease …, 2016 - nature.com
Infections with human papillomavirus (HPV) are common and transmitted by direct contact.
Although the great majority of infections resolve within 2 years, 13 phylogenetically related …

Human papillomavirus molecular biology and disease association

J Doorbar, N Egawa, H Griffin… - Reviews in medical …, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) have evolved over millions of years to propagate
themselves in a range of different animal species including humans. Viruses that have co …

[HTML][HTML] Opportunities and challenges for human papillomavirus vaccination in cancer

R Roden, PL Stern - Nature Reviews Cancer, 2018 - nature.com
The discovery of genotype 16 as the prototype oncogenic human papillomavirus (HPV)
initiated a quarter century of laboratory and epidemiological studies that demonstrated their …

Human papillomavirus in cervical cancer and oropharyngeal cancer: one cause, two diseases

TA Berman, JT Schiller - Cancer, 2017 - Wiley Online Library
Human papillomavirus (HPV) causes greater than 5% of cancers worldwide, including all
cervical cancers and an alarmingly increasing proportion of oropharyngeal cancers (OPCs) …