Over the past few decades, gene therapy has gained immense importance in medical
research as a promising treatment strategy for diseases such as cancer, AIDS, Alzheimer's …

Gene-based therapies have emerged as a new modality for combating a myriad of currently
incurable diseases. However, the fragile nature of gene therapeutics has significantly …

Highlights•Tumor cells increase their metabolic rates as well as glucose uptake to maintain
amplified proliferation,•Consequently, tumor cells switch from mitochondrial oxidative …

Background: Most of the active pharmaceutical ingredients discovered recently in
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …

Highlights•Tissue engineering may propose new hope for patients with injuries, or end-
stage organ failure.•Dendrimers have gained its importance in tissue engineering.•Recent …

Glioblastoma is one of the most rapaciously growing cancer within the brain with an average
lifespan of 12–15 months (5-year survival< 3–4%). Doxorubicin (DOX) is clinically utilized as …

Scientists are focusing immense attention on polymeric nanocarriers as a prominent delivery
vehicle for several biomedical applications including diagnosis of diseases, delivery of …

Ocular discomforts involve anterior/posterior-segment diseases, symptomatic distress and
associated inflammations and severe retinal disorders. Conventionally, the formulations …

Abstract Liposomes (LIP), nanoparticles (NP), dendrimers (DEN), and carbon nanotubes
(CNTs), represent eminent classes of drug delivery devices. A study was carried out …

With its rapid development in the past few decades, gene therapy has shown potential for
use as a standard clinical intervention for the treatment of several conditions, including …