Rare cell isolation and analysis in microfluidics

Y Chen, P Li, PH Huang, Y **e, JD Mai, L Wang… - Lab on a Chip, 2014‏ - pubs.rsc.org
Rare cells are low-abundance cells in a much larger population of background cells.
Conventional benchtop techniques have limited capabilities to isolate and analyze rare cells …

Circulating tumor cells: a review of present methods and the need to identify heterogeneous phenotypes

LM Millner, MW Linder, R Valdes - Annals of Clinical & Laboratory …, 2013‏ - annclinlabsci.org
The measurement and characterization of circulating tumor cells (CTCs) hold promise for
advancing personalized therapeutics. CTCs are the precursor to metastatic cancer and thus …

[HTML][HTML] Isolation of circulating tumor cells by dielectrophoresis

PRC Gascoyne, S Shim - Cancers, 2014‏ - mdpi.com
Dielectrophoresis (DEP) is an electrokinetic method that allows intrinsic dielectric properties
of suspended cells to be exploited for discrimination and separation. It has emerged as a …

Antibody-independent isolation of circulating tumor cells by continuous-flow dielectrophoresis

S Shim, K Stemke-Hale, AM Tsimberidou, J Noshari… - …, 2013‏ - pubs.aip.org
Circulating tumor cells (CTCs) are prognostic markers for the recurrence of cancer and may
carry molecular information relevant to cancer diagnosis. Dielectrophoresis (DEP) has been …

Correlations between the dielectric properties and exterior morphology of cells revealed by dielectrophoretic field‐flow fractionation

PRC Gascoyne, S Shim, J Noshari, FF Becker… - …, 2013‏ - Wiley Online Library
Although dielectrophoresis (DEP) has great potential for addressing clinical cell isolation
problems based on cell dielectric differences, a biological basis for predicting the DEP …

Dielectrophoretic applications for disease diagnostics using lab-on-a-chip platforms

EO Adekanmbi, SK Srivastava - Lab on a Chip, 2016‏ - pubs.rsc.org
Dielectrophoresis is a powerful technique used to distinguish distinct cellular identities in
heterogeneous cell populations and to monitor changes in the cell state without the need for …

Benchtop technologies for circulating tumor cells separation based on biophysical properties

WS Low, WAB Wan Abas - BioMed research international, 2015‏ - Wiley Online Library
Circulating tumor cells (CTCs) are tumor cells that have detached from primary tumor site
and are transported via the circulation system. The importance of CTCs as prognostic …

In-vitro bipolar nano-and microsecond electro-pulse bursts for irreversible electroporation therapies

MB Sano, CB Arena, MR DeWitt, D Saur, RV Davalos - Bioelectrochemistry, 2014‏ - Elsevier
Under the influence of external electric fields, cells experience a rapid potential buildup
across the cell membrane. Above a critical threshold of electric field strength, permanent cell …

Dielectrophoresis in cell characterization

EA Henslee - Electrophoresis, 2020‏ - Wiley Online Library
Many cellular functions are affected by and thus can be characterized by a cell's
electrophysiology. This has also been found to correspond to other biophysical parameters …

Dielectrophoretic manipulation of cancer cells and their electrical characterization

I Turcan, MA Olariu - ACS Combinatorial Science, 2020‏ - ACS Publications
Electromanipulation and electrical characterization of cancerous cells is becoming a topic of
high interest as the results reported to date demonstrate a good differentiation among …