Stimuli-responsive therapeutic metallodrugs

X Wang, X Wang, S **, N Muhammad, Z Guo - Chemical reviews, 2018 - ACS Publications
The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …

Optochemical control of biological processes in cells and animals

N Ankenbruck, T Courtney, Y Naro… - Angewandte Chemie …, 2018 - Wiley Online Library
Biological processes are naturally regulated with high spatial and temporal control, as is
perhaps most evident in metazoan embryogenesis. Chemical tools have been extensively …

Smart nanostructures for cargo delivery: uncaging and activating by light

M Karimi, P Sahandi Zangabad… - Journal of the …, 2017 - ACS Publications
Nanotechnology has begun to play a remarkable role in various fields of science and
technology. In biomedical applications, nanoparticles have opened new horizons, especially …

[ΒΙΒΛΙΟ][B] Photochemistry and photophysics: concepts, research, applications

V Balzani, P Ceroni, A Juris - 2014 - books.google.com
This textbook covers the spectrum from basic concepts of photochemistry and photophysics
to selected examples of current applications and research. Clearly structured, the first part of …

Recent progress in polymer-based platinum drug delivery systems

H **ao, L Yan, EM Dempsey, W Song, R Qi, W Li… - Progress in Polymer …, 2018 - Elsevier
Platinum drugs comprise of almost 50% of all currently used anticancer drugs. They are now
widely used in the clinical therapy of various solid tumors, including ovarian, head and neck …

PhotoCORMs: Light-triggered release of carbon monoxide from the coordination sphere of transition metal complexes for biological applications

U Schatzschneider - Inorganica Chimica Acta, 2011 - Elsevier
Carbon monoxide is now well-established as a small-molecule biological effector in the
human body. Metal–carbonyl complexes are a promising way to achieve safe and controlled …

Diazido platinum (IV) complexes for photoactivated anticancer chemotherapy

H Shi, C Imberti, PJ Sadler - Inorganic Chemistry Frontiers, 2019 - pubs.rsc.org
Diazido Pt (IV) complexes with a general formula [Pt (N3) 2 (L)(L′)(OR)(OR′)] are a new
generation of anticancer prodrugs designed for use in photoactivated chemotherapy. The …

Towards cancer cell-specific phototoxic organometallic rhenium (I) complexes

A Leonidova, V Pierroz, R Rubbiani, J Heier… - Dalton …, 2014 - pubs.rsc.org
Over the recent years, several Re (I) organometallic compounds have been shown to be
toxic to various cancer cell lines. However, these compounds lacked sufficient selectivity …

Photoswitchable antimetabolite for targeted photoactivated chemotherapy

C Matera, AMJ Gomila, N Camarero… - Journal of the …, 2018 - ACS Publications
The efficacy and tolerability of systemically administered anticancer agents are limited by
their off-target effects. Precise spatiotemporal control over their cytotoxic activity would allow …

[HTML][HTML] Targeted cancer therapy using compounds activated by light

P Dunkel, J Ilaš - Cancers, 2021 - mdpi.com
Simple Summary Cancer is among the leading causes of death, and cancer therapy suffers
from many drawbacks, the lack of selectivity being most noteworthy. In this review, we …