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Stimuli-responsive therapeutic metallodrugs
The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …
metal-based drugs for several decades, whereas problems such as drug-resistance and …
Optochemical control of biological processes in cells and animals
N Ankenbruck, T Courtney, Y Naro… - Angewandte Chemie …, 2018 - Wiley Online Library
Biological processes are naturally regulated with high spatial and temporal control, as is
perhaps most evident in metazoan embryogenesis. Chemical tools have been extensively …
perhaps most evident in metazoan embryogenesis. Chemical tools have been extensively …
Smart nanostructures for cargo delivery: uncaging and activating by light
Nanotechnology has begun to play a remarkable role in various fields of science and
technology. In biomedical applications, nanoparticles have opened new horizons, especially …
technology. In biomedical applications, nanoparticles have opened new horizons, especially …
[ΒΙΒΛΙΟ][B] Photochemistry and photophysics: concepts, research, applications
This textbook covers the spectrum from basic concepts of photochemistry and photophysics
to selected examples of current applications and research. Clearly structured, the first part of …
to selected examples of current applications and research. Clearly structured, the first part of …
Recent progress in polymer-based platinum drug delivery systems
Platinum drugs comprise of almost 50% of all currently used anticancer drugs. They are now
widely used in the clinical therapy of various solid tumors, including ovarian, head and neck …
widely used in the clinical therapy of various solid tumors, including ovarian, head and neck …
PhotoCORMs: Light-triggered release of carbon monoxide from the coordination sphere of transition metal complexes for biological applications
U Schatzschneider - Inorganica Chimica Acta, 2011 - Elsevier
Carbon monoxide is now well-established as a small-molecule biological effector in the
human body. Metal–carbonyl complexes are a promising way to achieve safe and controlled …
human body. Metal–carbonyl complexes are a promising way to achieve safe and controlled …
Diazido platinum (IV) complexes for photoactivated anticancer chemotherapy
H Shi, C Imberti, PJ Sadler - Inorganic Chemistry Frontiers, 2019 - pubs.rsc.org
Diazido Pt (IV) complexes with a general formula [Pt (N3) 2 (L)(L′)(OR)(OR′)] are a new
generation of anticancer prodrugs designed for use in photoactivated chemotherapy. The …
generation of anticancer prodrugs designed for use in photoactivated chemotherapy. The …
Towards cancer cell-specific phototoxic organometallic rhenium (I) complexes
A Leonidova, V Pierroz, R Rubbiani, J Heier… - Dalton …, 2014 - pubs.rsc.org
Over the recent years, several Re (I) organometallic compounds have been shown to be
toxic to various cancer cell lines. However, these compounds lacked sufficient selectivity …
toxic to various cancer cell lines. However, these compounds lacked sufficient selectivity …
Photoswitchable antimetabolite for targeted photoactivated chemotherapy
The efficacy and tolerability of systemically administered anticancer agents are limited by
their off-target effects. Precise spatiotemporal control over their cytotoxic activity would allow …
their off-target effects. Precise spatiotemporal control over their cytotoxic activity would allow …
[HTML][HTML] Targeted cancer therapy using compounds activated by light
Simple Summary Cancer is among the leading causes of death, and cancer therapy suffers
from many drawbacks, the lack of selectivity being most noteworthy. In this review, we …
from many drawbacks, the lack of selectivity being most noteworthy. In this review, we …