Dry eye management: targeting the ocular surface microenvironment

X Zhang, V Jeyalatha M, Y Qu, X He, S Ou, J Bu… - International journal of …, 2017 - mdpi.com
Dry eye can damage the ocular surface and result in mild corneal epithelial defect to
blinding corneal pannus formation and squamous metaplasia. Significant progress in the …

Dry eye syndrome: comprehensive etiologies and recent clinical trials

R Huang, C Su, L Fang, J Lu, J Chen… - International …, 2022 - Springer
Dry eye syndrome (DES) is multifactorial and likely to be a cause of concern more so than
ever given the rapid pace of modernization, which is directly associated with many of the …

Nanoceria-Mediated Cyclosporin A Delivery for Dry Eye Disease Management through Modulating Immune–Epithelial Crosstalk

W Cui, S Chen, T Hu, T Zhou, C Qiu, L Jiang… - ACS …, 2024 - ACS Publications
Dry eye disease (DED) affects a substantial worldwide population with increasing frequency.
Current single-targeting DED management is severely hindered by the existence of an …

A comprehensive insight on ocular pharmacokinetics

V Agrahari, A Mandal, V Agrahari, HM Trinh… - Drug delivery and …, 2016 - Springer
The eye is a distinctive organ with protective anatomy and physiology. Several
pharmacokinetics compartment models of ocular drug delivery have been developed for …

[HTML][HTML] A review on dry eye disease treatment: recent progress, diagnostics, and future perspectives

H Mondal, HJ Kim, N Mohanto, JP Jee - Pharmaceutics, 2023 - mdpi.com
Dry eye disease is a multifactorial disorder of the eye and tear film with potential damage to
the ocular surface. Various treatment approaches for this disorder aim to alleviate disease …

A review of the mechanism of action of cyclosporine A: the role of cyclosporine A in dry eye disease and recent formulation developments

LM Periman, FS Mah, PM Karpecki - Clinical Ophthalmology, 2020 - Taylor & Francis
Dry eye disease (DED) is a multifactorial disease of the ocular surface and tear film that has
gained awareness as a public health problem. Characteristics of DED include tear film …

[HTML][HTML] Elevated expression of matrix metalloproteinase-9 and inflammatory cytokines in keratoconus patients is inhibited by cyclosporine A

R Shetty, A Ghosh, RR Lim… - … & visual science, 2015 - tvst.arvojournals.org
Purpose.: The present study was designed to understand the role of inflammatory cytokines
secreted by corneal epithelial cells in keratoconus (KC) and the response to treatment with …

Dry eye syndrome

MA Javadi, S Feizi - Journal of ophthalmic & vision research, 2011 - pmc.ncbi.nlm.nih.gov
Our understanding of keratoconjunctivitis sicca (KCS), also known as dry eye syndrome, has
been changed over recent years. Until lately, the condition was thought to be merely due to …

The impact of dry eye disease treatment on patient satisfaction and quality of life: A review

JAP Gomes, RM Santo - The ocular surface, 2019 - Elsevier
Several aspects of the quality of life (QoL) and treatment satisfaction of patients with dry eye
disease (DED) may be underestimated. Ocular symptoms, which are assessed by validated …

Artificial tears potpourri: a literature review

M Moshirfar, K Pierson, K Hanamaikai… - Clinical …, 2014 - Taylor & Francis
Numerous brands and types of artificial tears are available on the market for the treatment of
dysfunctional tear syndrome. Past literature has focused on comparing the components of …