Macrophages are cells of the innate immunity constituting the mononuclear phagocyte
system and endowed with remarkable different roles essential for defense mechanisms …

“Asymptomatic” Malaria: A Chronic and Debilitating Infection That Should Be Treated | PLOS
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Innate immune receptors have a key role in immune surveillance by sensing
microorganisms and initiating protective immune responses. However, the innate immune …

Transition metals are required cofactors for many proteins that are critical for life, and their
concentration within cells is carefully maintained to avoid both deficiency and toxicity. To …

Abstract In sub-Saharan Africa, multidrug-resistant non-typhoidal Salmonella serovars are a
common cause of fatal bloodstream infection. Malnutrition is a predisposing factor, but the …

Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

The acute-phase response is triggered by the presence of infectious agents and danger
signals which indicate hazards for the integrity of the mammalian body. One central feature …

Nontyphoidal salmonellae (NTS) are a major cause of invasive (iNTS) disease in sub-
Saharan Africa, manifesting as bacteremia and meningitis. Available epidemiological data …

Background The objectives of this study were to determine the proportion of malaria,
bacteraemia, scrub typhus, leptospirosis, chikungunya and dengue among hospitalized …

Neutrophils are the most abundant leukocytes in human peripheral blood. They form the first
line of defense against invading foreign pathogens and might play a crucial role in malaria …