Selenium is an essential micronutrient that plays a crucial role in development and a wide
variety of physiological processes including effect immune responses. The immune system …

The endoplasmic reticulum (ER) is the major folding compartment for secreted and
membrane proteins and is the site of a specific chaperone system, the calnexin cycle, for …

The trace element selenium (Se) is an essential part of the human diet; moreover, increased
health risks have been observed with Se deficiency. A sufficiently high Se status is a …

Over 50 billion cells undergo apoptosis each day in an adult human to maintain immune
homeostasis. Hydrogen sulfide (H 2 S) is also required to safeguard the function of immune …

The site of protein folding and maturation for the majority of proteins that are secreted,
localized to the plasma membrane or targeted to endomembrane compartments is the …

Selenocysteine is a catalytic residue at the active site of all selenoenzymes in bacteria and
mammals, and it is incorporated into the polypeptide backbone by a co-translational process …

Selenium (Se) is an essential trace element that functions in the form of the 21st amino acid,
selenocysteine (Sec) in a defined set of proteins. Se deficiency is associated with …

Accumulation of genome and macromolecule damage is a hallmark of aging, age-
associated degeneration, and genome instability syndromes. Although processes of aging …

Significance: Selenoproteins incorporate the essential nutrient selenium into their
polypeptide chain. Seven members of this family reside in the endoplasmic reticulum (ER) …

Selenium (Se) is an essential micronutrient that functions in the body mainly in the form of
selenoproteins. The selenoprotein contains 25 members in humans that exhibit a number of …