Mismatch repair proficient (MMRp) tumors of colorectal origin are one of the prevalent yet
unpredictable clinical challenges. Despite earnest efforts, optimal treatment modalities have …

The use of biomarkers in breast cancer has significantly improved patient outcomes through
targeted therapies, such as hormone therapy, anti-Her2 therapy and CDK4/6 or PARP …

Background Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with no
clinically ideal biomarkers for early diagnosis. The objective of this study was to develop and …

Background The advancements in artificial intelligence (AI) technology for image recognition
were propelling molecular pathology research into a new era. Objective To summarize the …

Intratumoral immune profiles are related to prognosis and therapeutic efficacy, and could
result in personalized treatments based on biomarkers. To develop a multiplex, quantitative …

Two-photon imaging is a powerful method to record the activity of neuronal ensembles in the
intact animal brain. Here, we describe a protocol to run a recent analytical approach, CITE …

The Human Proteome Project (HPP), the flagship initiative of the Human Proteome
Organization (HUPO), has pursued two goals:(1) to credibly identify at least one isoform of …

Bioactive lipids, including lysophospholipids, sphingolipids, eicosanoids, and their
metabolites, hold promise as potential biomarkers for various diseases. Recent advances in …

Despite the successes of immunotherapy in cancer treatment over recent decades, less
than< 10%–20% cancer cases have demonstrated durable responses from immune …

In this paper, we explore the transformative role of artificial intelligence (AI) in the analysis
and transformation of biomedical images in the field of cancer immunotherapy. This review …