Plastin 3 in health and disease: a matter of balance
L Wolff, EA Strathmann, I Müller, D Mählich… - Cellular and Molecular …, 2021 - Springer
For a long time, PLS3 (plastin 3, also known as T-plastin or fimbrin) has been considered a
rather inconspicuous protein, involved in F-actin-binding and-bundling. However, in recent …
rather inconspicuous protein, involved in F-actin-binding and-bundling. However, in recent …
From pinocytosis to methuosis—fluid consumption as a risk factor for cell death
The volumes of a cell [cell volume (CV)] and its organelles are adjusted by osmoregulatory
processes. During pinocytosis, extracellular fluid volume equivalent to its CV is incorporated …
processes. During pinocytosis, extracellular fluid volume equivalent to its CV is incorporated …
β2 integrins impose a mechanical checkpoint on macrophage phagocytosis
Phagocytosis is an intensely physical process that depends on the mechanical properties of
both the phagocytic cell and its chosen target. Here, we employed differentially deformable …
both the phagocytic cell and its chosen target. Here, we employed differentially deformable …
Elasticity of podosome actin networks produces nanonewton protrusive forces
Actin filaments assemble into force-generating systems involved in diverse cellular
functions, including cell motility, adhesion, contractility and division. It remains unclear how …
functions, including cell motility, adhesion, contractility and division. It remains unclear how …
Pinching the cortex of live cells reveals thickness instabilities caused by myosin II motors
The cell cortex is a contractile actin meshwork, which determines cell shape and is essential
for cell mechanics, migration, and division. Because its thickness is below optical resolution …
for cell mechanics, migration, and division. Because its thickness is below optical resolution …
Extracellular matrix stiffness modulates host-bacteria interactions and antibiotic therapy of bacterial internalization
X Liu, K Zhu, X Duan, P Wang, Y Han, W Peng… - Biomaterials, 2021 - Elsevier
Pathogenic bacteria evolve multiple strategies to hijack host cells for intracellular survival
and persistent infections. Previous studies have revealed the intricate interactions between …
and persistent infections. Previous studies have revealed the intricate interactions between …
Pathogenic Huntingtin aggregates alter actin organization and cellular stiffness resulting in stalled clathrin-mediated endocytosis
Aggregation of mutant forms of Huntingtin is the underlying feature of neurodegeneration
observed in Huntington's disorder. In addition to neurons, cellular processes in non …
observed in Huntington's disorder. In addition to neurons, cellular processes in non …
[HTML][HTML] The endocytic protein machinery as an actin-driven membrane-remodeling machine
M Skruzny - European Journal of Cell Biology, 2022 - Elsevier
In clathrin-mediated endocytosis, a principal membrane trafficking route of all eukaryotic
cells, forces are applied to invaginate the plasma membrane and form endocytic vesicles …
cells, forces are applied to invaginate the plasma membrane and form endocytic vesicles …
Rapid adaptation of endocytosis, exocytosis, and eisosomes after an acute increase in membrane tension in yeast cells
During clathrin-mediated endocytosis (CME) in eukaryotes, actin assembly is required to
overcome large membrane tension and turgor pressure. However, the molecular …
overcome large membrane tension and turgor pressure. However, the molecular …
The actin cytoskeleton regulates danger-associated molecular pattern signaling and PEP1 RECEPTOR1 internalization
H Qian, X Zuo, Y Man, C Xu, P Luo, L Yao… - Plant …, 2025 - academic.oup.com
In plants, cytoskeletal proteins assemble into dynamic polymers that play numerous roles in
diverse fundamental cellular processes, including endocytosis, vesicle trafficking, and the …
diverse fundamental cellular processes, including endocytosis, vesicle trafficking, and the …