Responding to the opioid crisis in North America and beyond: recommendations of the Stanford–Lancet Commission
Executive summary The Stanford–Lancet Commission on the North American Opioid Crisis
was formed in response to soaring opioid-related morbidity and mortality in the USA and …
was formed in response to soaring opioid-related morbidity and mortality in the USA and …
The changing opioid crisis: development, challenges and opportunities
ND Volkow, C Blanco - Molecular psychiatry, 2021 - nature.com
The current opioid epidemic is one of the most severe public health crisis in US history.
Responding to it has been difficult due to its rapidly changing nature and the severity of its …
Responding to it has been difficult due to its rapidly changing nature and the severity of its …
Bias factor and therapeutic window correlate to predict safer opioid analgesics
Biased agonism has been proposed as a means to separate desirable and adverse drug
responses downstream of G protein-coupled receptor (GPCR) targets. Herein, we describe …
responses downstream of G protein-coupled receptor (GPCR) targets. Herein, we describe …
Quantifying the epidemic of prescription opioid overdose deaths
P Seth, RA Rudd, RK Noonan… - American journal of …, 2018 - ajph.aphapublications.org
In 2016, 63 632 persons died of a drug overdose in the United States; 66.4%(42 249)
involved an opioid. 1 Opioid-involved deaths include prescription opioid analgesics (eg …
involved an opioid. 1 Opioid-involved deaths include prescription opioid analgesics (eg …
[HTML][HTML] Treatment of overdose in the synthetic opioid era
P Skolnick - Pharmacology & therapeutics, 2022 - Elsevier
Overdose deaths are often viewed as the leading edge of the opioid epidemic which has
gripped the United States over the past two decades (Skolnick, 2018a). This emphasis is …
gripped the United States over the past two decades (Skolnick, 2018a). This emphasis is …
Prevention of prescription opioid misuse and projected overdose deaths in the United States
Importance Deaths due to opioid overdose have tripled in the last decade. Efforts to curb this
trend have focused on restricting the prescription opioid supply; however, the near-term …
trend have focused on restricting the prescription opioid supply; however, the near-term …
[HTML][HTML] Fentanyl test strips as an opioid overdose prevention strategy: findings from a syringe services program in the Southeastern United States
Background In 2016, the number of overdose deaths involving illicitly-manufactured fentanyl
(IMF) surpassed heroin and prescription opioid deaths in the United States for the first time …
(IMF) surpassed heroin and prescription opioid deaths in the United States for the first time …
Understanding links among opioid use, overdose, and suicide
Understanding Links among Opioid Use, Overdose, and Suicide | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
Steep increases in fentanyl-related mortality west of the Mississippi River: recent evidence from county and state surveillance
Background Overdose deaths from synthetic opioids (eg, fentanyl) increased 10-fold in the
United States from 2013 to 2018, despite such opioids being rare in illicit drug markets west …
United States from 2013 to 2018, despite such opioids being rare in illicit drug markets west …
Initial results of a drug checking pilot program to detect fentanyl adulteration in a Canadian setting
KW Tupper, K McCrae, I Garber, M Lysyshyn… - Drug and alcohol …, 2018 - Elsevier
Background Opioid overdose deaths in North America have been rising largely as a result of
fentanyl adulteration in the illegal drug supply. Drug checking is an established harm …
fentanyl adulteration in the illegal drug supply. Drug checking is an established harm …