RMST‐based multiple contrast tests in general factorial designs

M Munko, M Ditzhaus, D Dobler… - Statistics in …, 2024 - Wiley Online Library
Several methods in survival analysis are based on the proportional hazards assumption.
However, this assumption is very restrictive and often not justifiable in practice. Therefore …

Computation of the Mann–Whitney effect under parametric survival copula models

K Nakazono, YC Lin, GY Liao, R Uozumi, T Emura - Mathematics, 2024 - mdpi.com
The Mann–Whitney effect is a measure for comparing survival distributions between two
groups. The Mann–Whitney effect is interpreted as the probability that a randomly selected …

Estimation of the Mann–Whitney effect in the two-sample problem under dependent censoring

T Emura, JH Hsu - Computational Statistics & Data Analysis, 2020 - Elsevier
Abstract The Mann–Whitney effect is a nonparametric measure for comparing the
distribution between two groups, which can be estimated by right-censored data. However …

CASANOVA: Permutation inference in factorial survival designs

M Ditzhaus, J Genuneit, A Janssen, M Pauly - Biometrics, 2023 - Wiley Online Library
We propose inference procedures for general factorial designs with time‐to‐event
endpoints. Similar to additive Aalen models, null hypotheses are formulated in terms of …

Factorial survival analysis for treatment effects under dependent censoring

T Emura, M Ditzhaus, D Dobler… - Statistical Methods in …, 2024 - journals.sagepub.com
Factorial analyses offer a powerful nonparametric means to detect main or interaction effects
among multiple treatments. For survival outcomes, for example, from clinical trials, such …

A survival tree based on stabilized score tests for high-dimensional covariates

T Emura, WC Hsu, WC Chou - Journal of Applied Statistics, 2023 - Taylor & Francis
ABSTRACT A survival tree can classify subjects into different survival prognostic groups.
However, when data contains high-dimensional covariates, the two popular classification …

Inferring median survival differences in general factorial designs via permutation tests

M Ditzhaus, D Dobler, M Pauly - Statistical Methods in …, 2021 - journals.sagepub.com
Factorial survival designs with right-censored observations are commonly inferred by Cox
regression and explained by means of hazard ratios. However, in case of non-proportional …

Studentized permutation method for comparing two restricted mean survival times with small sample from randomized trials

M Ditzhaus, M Yu, J Xu - Statistics in medicine, 2023 - Wiley Online Library
Recent observations, especially in cancer immunotherapy clinical trials with time‐to‐event
outcomes, show that the commonly used proportional hazard assumption is often not …

Estimation of a new stress strength index for one parameter exponential family

TR Gupta, M Pauly, S Kumar - IEEE Transactions on Reliability, 2023 - ieeexplore.ieee.org
Stress-strength reliability is widely used in manufacturing industry for producing good quality
equipment. A new stress-strength index has been introduced when strengths of independent …