Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
Evolution of the human nervous system function, structure, and development
The nervous system—in particular, the brain and its cognitive abilities—is among humans'
most distinctive and impressive attributes. How the nervous system has changed in the …
most distinctive and impressive attributes. How the nervous system has changed in the …
Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v. 14.0)
H Mi, A Muruganujan, X Huang, D Ebert, C Mills… - Nature protocols, 2019 - nature.com
The PANTHER classification system (http://www. pantherdb. org) is a comprehensive system
that combines genomes, gene function classifications, pathways and statistical analysis …
that combines genomes, gene function classifications, pathways and statistical analysis …
Adaptive sequence divergence forged new neurodevelopmental enhancers in humans
Searches for the genetic underpinnings of uniquely human traits have focused on human-
specific divergence in conserved genomic regions, which reflects adaptive modifications of …
specific divergence in conserved genomic regions, which reflects adaptive modifications of …
PANTHER version 10: expanded protein families and functions, and analysis tools
H Mi, S Poudel, A Muruganujan… - Nucleic acids …, 2016 - academic.oup.com
PANTHER (P rotein An alysis TH rough E volutionary R elationships, http://pantherdb. org) is
a widely used online resource for comprehensive protein evolutionary and functional …
a widely used online resource for comprehensive protein evolutionary and functional …
Large-scale gene function analysis with the PANTHER classification system
The PANTHER (protein annotation through evolutionary relationship) classification system
(http://www. pantherdb. org/) is a comprehensive system that combines gene function …
(http://www. pantherdb. org/) is a comprehensive system that combines gene function …
Cortical evolution: judge the brain by its cover
To understand the emergence of human higher cognition, we must understand its biological
substrate—the cerebral cortex, which considers itself the crowning achievement of evolution …
substrate—the cerebral cortex, which considers itself the crowning achievement of evolution …
A genome-scan method to identify selected loci appropriate for both dominant and codominant markers: a Bayesian perspective
Identifying loci under natural selection from genomic surveys is of great interest in different
research areas. Commonly used methods to separate neutral effects from adaptive effects …
research areas. Commonly used methods to separate neutral effects from adaptive effects …
Insights into hominid evolution from the gorilla genome sequence
Gorillas are humans' closest living relatives after chimpanzees, and are of comparable
importance for the study of human origins and evolution. Here we present the assembly and …
importance for the study of human origins and evolution. Here we present the assembly and …
A map of recent positive selection in the human genome
The identification of signals of very recent positive selection provides information about the
adaptation of modern humans to local conditions. We report here on a genome-wide scan …
adaptation of modern humans to local conditions. We report here on a genome-wide scan …