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[HTML][HTML] Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine
Cancer is the second leading cause of mortality globally which remains a continuing threat
to human health today. Drug insensitivity and resistance are critical hurdles in cancer …
to human health today. Drug insensitivity and resistance are critical hurdles in cancer …
Recent advance in oxazole-based medicinal chemistry
HZ Zhang, ZL Zhao, CH Zhou - European journal of medicinal chemistry, 2018 - Elsevier
Oxazole compounds containing nitrogen and oxygen atoms in the five-membered aromatic
ring are readily able to bind with a variety of enzymes and receptors in biological systems …
ring are readily able to bind with a variety of enzymes and receptors in biological systems …
Interfacial defect passivation and stress release via multi-active-site ligand anchoring enables efficient and stable methylammonium-free perovskite solar cells
B Liu, H Bi, D He, L Bai, W Wang, H Yuan… - ACS Energy …, 2021 - ACS Publications
Interfacial trap-assisted non-radiative recombination and residual stress impede the further
increase of power conversion efficiency (PCE) and stability of the methylammonium-free …
increase of power conversion efficiency (PCE) and stability of the methylammonium-free …
[HTML][HTML] 1, 3, 4-Oxadiazole-containing hybrids as potential anticancer agents: Recent developments, mechanism of action and structure-activity relationships
Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently,
many anticancer drugs are available in the market that plays an important role in cancer …
many anticancer drugs are available in the market that plays an important role in cancer …
Anticancer, antimicrobial activities of quinoline based hydrazone analogues: Synthesis, characterization and molecular docking
Based on the biologically active heterocycle quinoline, a series (18a-p) of quinoline
hydrazone analogues were prepared, starting from 6-bromo/6-chloro-2-methyl-quinolin-4-yl …
hydrazone analogues were prepared, starting from 6-bromo/6-chloro-2-methyl-quinolin-4-yl …
Synthesis and characterization of new functionalized chitosan and its antimicrobial and in-vitro release behavior from topical gel
Recently, chitosan and its derivatives have been gaining more attention due to their high
integration into various biomedical applications. Herein, a new chitosan derivative was …
integration into various biomedical applications. Herein, a new chitosan derivative was …
Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail …
The hydrophobic and the hydrophilic rims in the active site of human carbonic anhydrase IX
(hCA IX) which as well contains a zinc ion as part of the catalytic core, were simultaneously …
(hCA IX) which as well contains a zinc ion as part of the catalytic core, were simultaneously …
An understanding of mechanism-based approaches for 1, 3, 4-oxadiazole scaffolds as cytotoxic agents and enzyme inhibitors
The world's health system is plagued by cancer and a worldwide effort is underway to find
new drugs to treat cancer. There has been a significant improvement in understanding the …
new drugs to treat cancer. There has been a significant improvement in understanding the …
A green synthesis, DFT calculations, and molecular docking study of some new indeno [2, 1-b] quinoxalines containing thiazole moiety
A series of new indenoquinoxaline-thiazole hybrids were synthesized by combining
indenoquinoxaline thiosemicarbazone with appropriate hydrazonoyl chlorides or α-halo …
indenoquinoxaline thiosemicarbazone with appropriate hydrazonoyl chlorides or α-halo …
Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents
New benzimidazole derivatives were synthesized and assessed for antimicrobial efficacy
toward Escherichia coli, Bacillus cereus, Staphylococcus aureus, Candida albicans and …
toward Escherichia coli, Bacillus cereus, Staphylococcus aureus, Candida albicans and …