[HTML][HTML] Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine

YT Lee, YJ Tan, CE Oon - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Cancer is the second leading cause of mortality globally which remains a continuing threat
to human health today. Drug insensitivity and resistance are critical hurdles in cancer …

Recent advance in oxazole-based medicinal chemistry

HZ Zhang, ZL Zhao, CH Zhou - European journal of medicinal chemistry, 2018 - Elsevier
Oxazole compounds containing nitrogen and oxygen atoms in the five-membered aromatic
ring are readily able to bind with a variety of enzymes and receptors in biological systems …

Interfacial defect passivation and stress release via multi-active-site ligand anchoring enables efficient and stable methylammonium-free perovskite solar cells

B Liu, H Bi, D He, L Bai, W Wang, H Yuan… - ACS Energy …, 2021 - ACS Publications
Interfacial trap-assisted non-radiative recombination and residual stress impede the further
increase of power conversion efficiency (PCE) and stability of the methylammonium-free …

[HTML][HTML] 1, 3, 4-Oxadiazole-containing hybrids as potential anticancer agents: Recent developments, mechanism of action and structure-activity relationships

S Nayak, SL Gaonkar, EA Musad… - Journal of Saudi Chemical …, 2021 - Elsevier
Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently,
many anticancer drugs are available in the market that plays an important role in cancer …

Anticancer, antimicrobial activities of quinoline based hydrazone analogues: Synthesis, characterization and molecular docking

KD Katariya, SR Shah, D Reddy - Bioorganic chemistry, 2020 - Elsevier
Based on the biologically active heterocycle quinoline, a series (18a-p) of quinoline
hydrazone analogues were prepared, starting from 6-bromo/6-chloro-2-methyl-quinolin-4-yl …

Synthesis and characterization of new functionalized chitosan and its antimicrobial and in-vitro release behavior from topical gel

AE Mohamed, WE Elgammal, AM Eid… - International Journal of …, 2022 - Elsevier
Recently, chitosan and its derivatives have been gaining more attention due to their high
integration into various biomedical applications. Herein, a new chitosan derivative was …

Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail …

HO Tawfik, A Petreni, CT Supuran… - European journal of …, 2022 - Elsevier
The hydrophobic and the hydrophilic rims in the active site of human carbonic anhydrase IX
(hCA IX) which as well contains a zinc ion as part of the catalytic core, were simultaneously …

A green synthesis, DFT calculations, and molecular docking study of some new indeno [2, 1-b] quinoxalines containing thiazole moiety

AM Abdallah, SM Gomha, MEA Zaki… - Journal of Molecular …, 2023 - Elsevier
A series of new indenoquinoxaline-thiazole hybrids were synthesized by combining
indenoquinoxaline thiosemicarbazone with appropriate hydrazonoyl chlorides or α-halo …

Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents

NS El-Gohary, MI Shaaban - European journal of medicinal chemistry, 2017 - Elsevier
New benzimidazole derivatives were synthesized and assessed for antimicrobial efficacy
toward Escherichia coli, Bacillus cereus, Staphylococcus aureus, Candida albicans and …