Design and application of fluorescent probes to detect cellular physical microenvironments

J Ma, R Sun, K ** and cancer development
JH Ahn, ES Davis, TA Daugird, S Zhao, IY Quiroga… - Nature, 2021‏ - nature.com
The development of cancer is intimately associated with genetic abnormalities that target
proteins with intrinsically disordered regions (IDRs). In human haematological malignancies …

Caveat fluorophore: an insiders' guide to small-molecule fluorescent labels

JB Grimm, LD Lavis - Nature Methods, 2022‏ - nature.com
The last three decades have brought a revolution in fluorescence microscopy. The
development of new microscopes, fluorescent labels and analysis techniques has pushed …

Ultra-photostable small-molecule dyes facilitate near-infrared biophotonics

K Yan, Z Hu, P Yu, Z He, Y Chen, J Chen, H Sun… - Nature …, 2024‏ - nature.com
Long-wavelength, near-infrared small-molecule dyes are attractive in biophotonics.
Conventionally, they rely on expanded aromatic structures for redshift, which comes at the …

Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020‏ - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Optimized red-absorbing dyes for imaging and sensing

JB Grimm, AN Tkachuk, R Patel… - Journal of the …, 2023‏ - ACS Publications
Rhodamine dyes are excellent scaffolds for develo** a broad range of fluorescent probes.
A key property of rhodamines is their equilibrium between a colorless lactone and …