Molecules with at least one unpaired electron in their outermost shell are known as free
radicals. Free radical molecules are produced either within our bodies or by external …

Aging and associated neurodegenerative diseases are accompanied by the decline of
several brain functions including cognitive abilities. Progressive deleterious changes at …

Background Alzheimer's disease (AD) is the most prevalent dementia, affecting a large
number of populations. Despite being under scrutiny for decades, an effective therapeutic …

Microtubule affinity regulating kinase 4 (MARK4) is known to hyperphosphorylate tau
protein, which subsequently causes Alzheimer's disease (AD). MARK4 is a well-validated …

(1) Background: Epilepsy is one of the most common chronic neurological disorders in
childhood. Complementary and alternative medicine (CAM) use is highly prevalent in …

Accumulation of Aβ42 peptides forming plaque in various regions of the brain is a hallmark
of Alzheimer's disease (AD) progression. However, to date, there is no effective …

Objectives: Describe the clinical indications for the use of the botanical Bacopa monnieri.
Discuss possible mechanisms of action for Bacopa monnieri. Review adverse effects and …

Drug development for Alzheimer's disease, the leading cause of dementia, has been a long-
standing challenge. Saponins, which are steroid or triterpenoid glycosides with various …

Parkinson's disease is a chronic and gradually progressive neurodegenerative disorder
triggered due to the loss of dopamine-releasing neurons in the region of substantia nigra …

This study aims to summarize the effects of herbs on dementia and assess the strength of
evidence. Six international and local databases were searched from inception to October …