Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators
of vascular morphogenesis and function during development, cardiovascular homeostasis …

The focus of this review is to provide an overview of the current state of knowledge of
molecular mechanisms/processes that control differentiation of vascular smooth muscle cells …

The blood–brain barrier (BBB) consists of specific physical barriers, enzymes and
transporters, which together maintain the necessary extracellular environment of the central …

Platelet-derived growth factor (PDGF) is a major mitogen for connective tissue cells and
certain other cell types. It is a dimeric molecule consisting of disulfide-bonded, structurally …

Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) have served as
prototypes for growth factor and receptor tyrosine kinase function for more than 25 years …

Platelet-derived growth factor (PDGF)–B–deficient mouse embryos were found to lack
microvascular pericytes, which normally form part of the capillary wall, and they developed …

Interactions between endothelial cells and mural cells (pericytes and vascular smooth
muscle cells) in the blood vessel wall have recently come into focus as central processes in …

Pericytes play a key role in the development of cerebral microcirculation. The exact role of
pericytes in the neurovascular unit in the adult brain and during brain aging remains …

Blood vessels are composed of two interacting cell types. Endothelial cells form the inner
lining of the vessel wall, and perivascular cells—referred to as pericytes, vascular smooth …

Development of a vascular system involves the assembly of two principal cell types–
endothelial cells and vascular smooth muscle cells/pericytes (vSMC/PC)–into many different …