Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain

JA Letts, LA Sazanov - Nature structural & molecular biology, 2017 - nature.com
The oxidative phosphorylation electron transport chain (OXPHOS-ETC) of the inner
mitochondrial membrane is composed of five large protein complexes, named CI–CV. These …

[HTML][HTML] Cytochrome b6f–Orchestrator of photosynthetic electron transfer

LA Malone, MS Proctor, A Hitchcock, CN Hunter… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Cytochrome b 6 f (cytb 6 f) lies at the heart of the light-dependent reactions of oxygenic
photosynthesis, where it serves as a link between photosystem II (PSII) and photosystem I …

The architecture of respiratory supercomplexes

JA Letts, K Fiedorczuk, LA Sazanov - Nature, 2016 - nature.com
Mitochondrial electron transport chain complexes are organized into supercomplexes
responsible for carrying out cellular respiration. Here we present three architectures of …

[HTML][HTML] Structure of mammalian respiratory supercomplex I1III2IV1

M Wu, J Gu, R Guo, Y Huang, M Yang - Cell, 2016 - cell.com
The mammalian respiratory chain complexes assemble into supercomplexes (SCs) and
reside in the inner mitochondrial membrane to transfer electrons and establish the proton …

Structures of Tetrahymena's respiratory chain reveal the diversity of eukaryotic core metabolism

L Zhou, M Maldonado, A Padavannil, F Guo, JA Letts - Science, 2022 - science.org
Respiration is a core biological energy–converting process whose last steps are carried out
by a chain of multisubunit complexes in the inner mitochondrial membrane. To probe the …

Molecular mechanisms of superoxide production by the mitochondrial respiratory chain

S Dröse, U Brandt - … : nuclear-encoded genes, enzyme regulation, and …, 2012 - Springer
The mitochondrial respiratory chain is a major source of reactive oxygen species (ROS) in
eukaryotic cells. Mitochondrial ROS production associated with a dysfunction of respiratory …

[책][B] Bioenergetics

DG Nicholls - 2013 - books.google.com
Extensively revised, the fourth edition of this highly successful book takes into account the
many newly determined protein structures that provide molecular insight into chemiosmotic …

Catalytic Reactions and Energy Conservation in the Cytochrome bc1 and b6f Complexes of Energy-Transducing Membranes

M Sarewicz, S Pintscher, R Pietras, A Borek… - Chemical …, 2021 - ACS Publications
This review focuses on key components of respiratory and photosynthetic energy-
transduction systems: the cytochrome bc 1 and b 6 f (Cyt bc 1/b 6 f) membranous …

[HTML][HTML] Superoxide generation by complex III: from mechanistic rationales to functional consequences

L Bleier, S Dröse - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2013 - Elsevier
Apart from complex I (NADH: ubiquinone oxidoreductase) the mitochondrial cytochrome bc
1 complex (complex III; ubiquinol: cytochrome c oxidoreductase) has been identified as the …

An electron transfer path connects subunits of a mycobacterial respiratory supercomplex

H Gong, J Li, A Xu, Y Tang, W Ji, R Gao, S Wang, L Yu… - Science, 2018 - science.org
INTRODUCTION Cellular respiration is a core feature in the metabolism of many organisms
that allows for the generation of a proton gradient across a membrane. During respiration …