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Epstein–Barr virus and multiple sclerosis
Epstein–Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-
established causal role in several cancers. Recent studies have provided compelling …
established causal role in several cancers. Recent studies have provided compelling …
Genetics of multiple sclerosis: lessons from polygenicity
Large-scale map** studies have identified 236 independent genetic variants associated
with an increased risk of multiple sclerosis. However, none of these variants are found …
with an increased risk of multiple sclerosis. However, none of these variants are found …
Causal role of high body mass index in multiple chronic diseases: a systematic review and meta-analysis of Mendelian randomization studies
Background Obesity is a worldwide epidemic that has been associated with a plurality of
diseases in observational studies. The aim of this study was to summarize the evidence from …
diseases in observational studies. The aim of this study was to summarize the evidence from …
Vitamin D and human health: evidence from Mendelian randomization studies
A Fang, Y Zhao, P Yang, X Zhang… - European journal of …, 2024 - Springer
We summarized the current evidence on vitamin D and major health outcomes from
Mendelian randomization (MR) studies. PubMed and Embase were searched for original …
Mendelian randomization (MR) studies. PubMed and Embase were searched for original …
Health effects of vitamin D supplementation: lessons learned from randomized controlled trials and mendelian randomization studies
R Bouillon, MS LeBoff, RE Neale - Journal of Bone and Mineral …, 2023 - academic.oup.com
Vitamin D plays an important role in calcium homeostasis and many cellular processes.
Although vitamin D supplements are widely recommended for community‐dwelling adults …
Although vitamin D supplements are widely recommended for community‐dwelling adults …
Mendelian randomization as a tool to gain insights into the mosaic causes of autoimmune diseases
C Chen, P Wang, RD Zhang, Y Fang, LQ Jiang… - Autoimmunity …, 2022 - Elsevier
Autoimmune diseases (ADs) are a broad range of disorders which are characterized by long-
term inflammation and tissue damage arising from an immune response against one's own …
term inflammation and tissue damage arising from an immune response against one's own …
The role of gut microbiome in the pathogenesis of multiple sclerosis and related disorders
Multiple sclerosis (MS) is a chronic, progressive neuroinflammatory disease with a complex
pathophysiological background. A variety of diverse factors have been attributed to the …
pathophysiological background. A variety of diverse factors have been attributed to the …
Causal relationship between multiple sclerosis and cortical structure: a Mendelian randomization study
D Sun, R Wang, Q Du, Y Zhang, H Chen, Z Shi… - Journal of translational …, 2024 - Springer
Background Observational studies have suggested an association between multiple
sclerosis (MS) and cortical structure, but the results have been inconsistent. Objective We …
sclerosis (MS) and cortical structure, but the results have been inconsistent. Objective We …
Effects of vitamin D and body mass index on disease risk and relapse hazard in multiple sclerosis: a mendelian randomization study
Background and Objectives Decreased vitamin D levels and obesity are associated with an
increased risk for multiple sclerosis (MS). However, whether they also affect the disease …
increased risk for multiple sclerosis (MS). However, whether they also affect the disease …
Mendelian randomization as a tool for causal inference in human nutrition and metabolism
SC Larsson - Current opinion in lipidology, 2021 - journals.lww.com
Mendelian randomization can be used as a tool to improve causal inference in
observational studies assessing the role of nutritional factors and metabolites in health and …
observational studies assessing the role of nutritional factors and metabolites in health and …