[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
Overview of nanoparticulate strategies for solubility enhancement of poorly soluble drugs
KU Khan, MU Minhas, SF Badshah, M Suhail, A Ahmad… - Life Sciences, 2022 - Elsevier
Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …
industries. By some estimation, 70–90% drug candidates in development stage while up-to …
Carbon dot therapeutic platforms: administration, distribution, metabolism, excretion, toxicity, and therapeutic potential
Ultrasmall nanoparticles are often grouped under the broad umbrella term of “nanoparticles”
when reported in the literature. However, for biomedical applications, their small sizes give …
when reported in the literature. However, for biomedical applications, their small sizes give …
Amorphous solid dispersions: An update for preparation, characterization, mechanism on bioavailability, stability, regulatory considerations and marketed products
Amorphous solid dispersions (ASDs) are being employed frequently to improve
bioavailability of poorly soluble molecules by enhancing the rate and extant of dissolution in …
bioavailability of poorly soluble molecules by enhancing the rate and extant of dissolution in …
Beneath the skin: a review of current trends and future prospects of transdermal drug delivery systems
The ideal drug delivery system has a bioavailability comparable to parenteral dosage forms
but is as convenient and easy to use for the patient as oral solid dosage forms. In recent …
but is as convenient and easy to use for the patient as oral solid dosage forms. In recent …
Recent progress in nanotechnology-based drug carriers for resveratrol delivery
C Li, Z Wang, H Lei, D Zhang - Drug delivery, 2023 - Taylor & Francis
Resveratrol is a polyphenol with diverse pharmacological activities, but its clinical efficacy is
limited due to low solubility/permeability, light-induced isomerization, auto-oxidation, and …
limited due to low solubility/permeability, light-induced isomerization, auto-oxidation, and …
Scale‐up of electrospinning technology: Applications in the pharmaceutical industry
Recently, electrospinning (ES) of fibers has been shown to be an attractive strategy for drug
delivery. One of the main features of ES is that a wide variety of drugs can be loaded into the …
delivery. One of the main features of ES is that a wide variety of drugs can be loaded into the …
Nanocrystals of poorly soluble drugs: drug bioavailability and physicochemical stability
Many approaches have been developed over time to overcome the bioavailability limitations
of poorly soluble drugs. With the advances in nanotechnology in recent decades, science …
of poorly soluble drugs. With the advances in nanotechnology in recent decades, science …
The role of functional excipients in solid oral dosage forms to overcome poor drug dissolution and bioavailability
Many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution
rates in aqueous environments such as the luminal fluids of the gastrointestinal tract. The …
rates in aqueous environments such as the luminal fluids of the gastrointestinal tract. The …
Co-amorphous drug formulations in numbers: Recent advances in co-amorphous drug formulations with focus on co-formability, molar ratio, preparation methods …
Co-amorphous drug delivery systems (CAMS) are characterized by the combination of two
or more (initially crystalline) low molecular weight components that form a homogeneous …
or more (initially crystalline) low molecular weight components that form a homogeneous …