Membrane targeting cationic antimicrobial peptides

D Ciumac, H Gong, X Hu, JR Lu - Journal of colloid and interface science, 2019 - Elsevier
Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …

Langmuir monolayer techniques for the investigation of model bacterial membranes and antibiotic biodegradation mechanisms

M Rojewska, W Smułek, E Kaczorek, K Prochaska - Membranes, 2021 - mdpi.com
The amounts of antibiotics of anthropogenic origin released and accumulated in the
environment are known to have a negative impact on local communities of microorganisms …

The multifaceted antibacterial mechanisms of the pioneering peptide antibiotics tyrocidine and gramicidin S

M Wenzel, M Rautenbach, JA Vosloo, T Siersma… - MBio, 2018 - Am Soc Microbiol
Cyclic β-sheet decapeptides from the tyrocidine group and the homologous gramicidin S
were the first commercially used antibiotics, yet it remains unclear exactly how they kill …

A how-to guide for mode of action analysis of antimicrobial peptides

AB Schäfer, M Wenzel - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
Antimicrobial peptides (AMPs) are a promising alternative to classical antibiotics in the fight
against multi-resistant bacteria. They are produced by organisms from all domains of life and …

Microcin J25 inhibits ubiquinol oxidase activity of purified cytochrome bd-I from Escherichia coli

AE Galván, MC Chalón, NSR Colombo… - Biochimie, 2019 - Elsevier
Abstract Microcin J25 (MccJ25), an antimicrobial peptide, targets the respiratory chain but
the exact mechanism by which it does so remains unclear. Here, we reveal that MccJ25 is …

A bactericide peptide changing the static and dilatational surface elasticity properties of zwitterionic lipids at the air-water interface: Relationship with the …

HJA Santana, L Caseli - Biophysical Chemistry, 2021 - Elsevier
In this paper, we studied how different hydrophilicity degrees of the polar groups of the lipids
dipalmitoylphosphatidylcholine (DPPC) and dipalmitoyl phosphatidylethanolamine (DPPE) …

[HTML][HTML] Bacteriocin enterocin CRL35 is a modular peptide that induces non-bilayer states in bacterial model membranes

CM Amado, CJ Minahk, E Cilli, RG Oliveira… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The mechanism of action of the anti-Listeria peptide enterocin CRL35 was studied with
biophysical tools by using lipid mixtures that mimicked Gram-positive plasma membranes …

Impairment of the class IIa bacteriocin receptor function and membrane structural changes are associated to enterocin CRL35 high resistance in Listeria …

E Masias, FG Dupuy, PR da Silva Sanches… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Enterocin CRL35 is a class IIa bacteriocin with anti-Listeria activity. Resistance
to these peptides has been associated with either the downregulation of the receptor …

Incorporation of bacitracin in Langmuir films of phospholipids at the air-water interface

JC Rodrigues, L Caseli - Thin Solid Films, 2017 - Elsevier
Abstract Properties of microbicide drugs are believed to be associated to their interactions
with biointerfaces such as cell membranes, encouraging research on the identification of …

Interaction of cysteine and its derivatives with monolayers of dipalmitoylphosphatidylcholine

JM Arias, SB Díaz, AB Altabef, FG Dupuy - Colloids and Surfaces B …, 2019 - Elsevier
Molecular interactions between l-cysteine (Cys) and its ester derivatives (Cys x); l-cysteine
ethyl ester (CE), l-cysteine methyl ester (CM) and N-acetyl l-cysteine (NAC) with 1, 2 …