Minor cannabinoids: Biosynthesis, molecular pharmacology and potential therapeutic uses

KB Walsh, AE McKinney, AE Holmes - Frontiers in pharmacology, 2021 - frontiersin.org
The medicinal use of Cannabis sativa L. can be traced back thousands of years to ancient
China and Egypt. While marijuana has recently shown promise in managing chronic pain …

Synthetic cannabinoids: a pharmacological and toxicological overview

R Roque-Bravo, RS Silva, RF Malheiro… - Annual review of …, 2023 - annualreviews.org
Synthetic cannabinoids (SCs) are a chemically diverse group of new psychoactive
substances (NPSs) that target the endocannabinoid system, triggering a plethora of actions …

The why behind the high: determinants of neurocognition during acute cannabis exposure

JG Ramaekers, NL Mason, L Kloft… - Nature Reviews …, 2021 - nature.com
Acute cannabis intoxication may induce neurocognitive impairment and is a possible cause
of human error, injury and psychological distress. One of the major concerns raised about …

The synthetic cannabinoids menace: a review of health risks and toxicity

A Alzu'bi, F Almahasneh, R Khasawneh… - European Journal of …, 2024 - Springer
Synthetic cannabinoids (SCs) are chemically classified as psychoactive substances that
target the endocannabinoid system in many body organs. SCs can initiate …

An emerging trend in novel psychoactive substances (NPSs): designer THC

C Caprari, E Ferri, MA Vandelli, C Citti… - Journal of cannabis …, 2024 - Springer
Since its discovery as one of the main components of cannabis and its affinity towards the
cannabinoid receptor CB1, serving as a means to exert its psychoactivity, Δ9 …

[HTML][HTML] Cannabis as a source of approved drugs: A new look at an old problem

A Gabarin, L Yarmolinsky, A Budovsky, B Khalfin… - Molecules, 2023 - mdpi.com
Cannabis plants have been used in medicine since ancient times. They are well known for
their anti-diabetic, anti-inflammatory, neuroprotective, anti-cancer, anti-oxidative, anti …

Shifting North American drug markets and challenges for the system of care

RM Krausz, JN Westenberg, N Mathew, G Budd… - International Journal of …, 2021 - Springer
Drug markets are dynamic systems which change based on demand, competition,
legislation and revenue. Shifts that are not met with immediate and appropriate responses …

Cannabis use disorder and dissociation: A report from a prospective first-episode psychosis study

V Ricci, F Ceci, F Di Carlo, A Lalli, L Ciavoni… - Drug and alcohol …, 2021 - Elsevier
Background Cannabis is the most used recreational drug worldwide. Its use can increase
the risk of develo** psychotic disorders and exacerbate their course. However, the …

[HTML][HTML] Synaptic changes induced by cannabinoid drugs and cannabis use disorder

SM Augustin, DM Lovinger - Neurobiology of disease, 2022 - Elsevier
The legalization of cannabis in many countries, as well as the decrease in perceived risks of
cannabis, have contributed to the increase in cannabis use medicinally and recreationally …

[HTML][HTML] Therapeutic potential of cannabinoids in glaucoma

T Lindner, D Schmidl, L Peschorn, V Pai… - Pharmaceuticals, 2023 - mdpi.com
Glaucoma is a leading cause of irreversible blindness worldwide. To date, intraocular
pressure (IOP) is the only modifiable risk factor in glaucoma treatment, but even in treated …